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Assessment of Exposure-Response Functions for Rocket-Emission Toxicants.

PB98159874

Publication Date	1998
Page Count	228
Abstract	The Air Force has developed a probabilistic health-risk model, the Launch Area Toxic Risk Analysis (LATRA) model, to assist commanders in determining the risks to military personnel and civilians from exposure to emissions from normal and failed missile and space rocket launches. The Air Force Space Command requested that the National Research Council (NRC) independently review the toxicological components of LATRA to ensure their appropriateness. Specifically, the NRC was asked to focus on the toxicity of the three major rocket emissions -- hydrogen chloride (HCI), nitrogen dioxide (NO2), and nitric acid (HNO3) and several characteristics of the exposure-response components of LATRA, including identification of sensitive populations; definition of mild, moderate, and severe health effects; selection of independent variable in the exposure-response model; choice of analytic form for the exposure-response model (e.g., lognormal or probit) for each of the emissions; quantification of exposure-response model for each of the emissions; and representation and propagation of the uncertainties associated with the models. This report presents the subcommittee's evaluations, conclusions, and recommendations.
Keywords	Rocket exhaust Exhaust emission Toxic substances Risk assessment Environmental exposure Dose-response relationships Hydrogen chloride Nitrogen dioxide Nitric acid Rocket launching Plumes Environmental transport Toxicity Public health Human populations Health hazards Health effects Sensitivity analysis Uncertainty analysis Mathematical models LATRA(Launch Area Toxic Risk Analysis)
Source Agency	National Academy of Science National Research Council
Corporate Authors	National Research Council, Washington, DC. Committee on Toxicology.; Department of Defense, Washington, DC.
Supplemental Notes	Library of Congress card catalog no. 98-86245. See also AD-A332950. Sponsored by Department of Defense, Washington, DC.
Document Type	Technical Report
NTIS Issue Number	199821

Assessment of Exposure-Response Functions for Rocket-Emission Toxicants.

Assessment of Exposure-Response Functions for Rocket-Emission Toxicants.
PB98159874

Publication Date	1998
Page Count	228
Abstract	The Air Force has developed a probabilistic health-risk model, the Launch Area Toxic Risk Analysis (LATRA) model, to assist commanders in determining the risks to military personnel and civilians from exposure to emissions from normal and failed missile and space rocket launches. The Air Force Space Command requested that the National Research Council (NRC) independently review the toxicological components of LATRA to ensure their appropriateness. Specifically, the NRC was asked to focus on the toxicity of the three major rocket emissions -- hydrogen chloride (HCI), nitrogen dioxide (NO2), and nitric acid (HNO3) and several characteristics of the exposure-response components of LATRA, including identification of sensitive populations; definition of mild, moderate, and severe health effects; selection of independent variable in the exposure-response model; choice of analytic form for the exposure-response model (e.g., lognormal or probit) for each of the emissions; quantification of exposure-response model for each of the emissions; and representation and propagation of the uncertainties associated with the models. This report presents the subcommittee's evaluations, conclusions, and recommendations.
Keywords	Rocket exhaust Exhaust emission Toxic substances Risk assessment Environmental exposure Dose-response relationships Hydrogen chloride Nitrogen dioxide Nitric acid Rocket launching Plumes Environmental transport Toxicity Public health Human populations Health hazards Health effects Sensitivity analysis Uncertainty analysis Mathematical models LATRA(Launch Area Toxic Risk Analysis)
Source Agency	National Academy of Science National Research Council
Corporate Authors	National Research Council, Washington, DC. Committee on Toxicology.; Department of Defense, Washington, DC.
Supplemental Notes	Library of Congress card catalog no. 98-86245. See also AD-A332950. Sponsored by Department of Defense, Washington, DC.
Document Type	Technical Report
NTIS Issue Number	199821