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Dose-Response Assessment Issues in Occupational Mortality Studies.

PB95269908

Publication Date	1995
Personal Author	Hertz-Picciotto, I.; Lee, J. T.; Arrighi, H. M.
Page Count	24
Abstract	This project examined absenteeism as a surrogate for ill health and its usefulness in the context of the different survival problem. The data came from an occupational cohort study of arsenic (7440382) and lung cancer. The cohort consisted of all white male workers employed for 1 year or more between 1940 and 1964 at a copper smelter in Tacoma, Washington. After controlling for the level of current exposure, age at hire and year at hire, the risk of having a 30 day or longer absence was generally higher with increased level of cumulative exposure. In contrast, current exposure level shows an inverse relationship with absence. The mortality analysis suggests that a recent absence of more than 30 days was associated with a higher risk of death from respiratory cancer among employees exposed to arsenic. The authors caution that information on absenteeism without knowledge of the reasons for the absence is not in and of itself in such studies.
Keywords	Mortality Occupational safety and health Lungs Cancer Epidemiology Cohort studies Respirator system disorders Survival analysis Cause of dealth
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	44G - Environmental & Occupational Factors 57U - Public Health & Industrial Medicine
Corporate Authors	North Carolina Univ. at Chapel Hill. Dept. of Epidemiology.; National Inst. for Occupational Safety and Health, Cincinnati, OH.
Supplemental Notes	Sponsored by National Inst. for Occupational Safety and Health, Cincinnati, OH.
Document Type	Technical Report
Title Note	Final rept.
NTIS Issue Number	199523

Dose-Response Assessment Issues in Occupational Mortality Studies.

Dose-Response Assessment Issues in Occupational Mortality Studies.
PB95269908

Publication Date	1995
Personal Author	Hertz-Picciotto, I.; Lee, J. T.; Arrighi, H. M.
Page Count	24
Abstract	This project examined absenteeism as a surrogate for ill health and its usefulness in the context of the different survival problem. The data came from an occupational cohort study of arsenic (7440382) and lung cancer. The cohort consisted of all white male workers employed for 1 year or more between 1940 and 1964 at a copper smelter in Tacoma, Washington. After controlling for the level of current exposure, age at hire and year at hire, the risk of having a 30 day or longer absence was generally higher with increased level of cumulative exposure. In contrast, current exposure level shows an inverse relationship with absence. The mortality analysis suggests that a recent absence of more than 30 days was associated with a higher risk of death from respiratory cancer among employees exposed to arsenic. The authors caution that information on absenteeism without knowledge of the reasons for the absence is not in and of itself in such studies.
Keywords	Mortality Occupational safety and health Lungs Cancer Epidemiology Cohort studies Respirator system disorders Survival analysis Cause of dealth
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	44G - Environmental & Occupational Factors 57U - Public Health & Industrial Medicine
Corporate Authors	North Carolina Univ. at Chapel Hill. Dept. of Epidemiology.; National Inst. for Occupational Safety and Health, Cincinnati, OH.
Supplemental Notes	Sponsored by National Inst. for Occupational Safety and Health, Cincinnati, OH.
Document Type	Technical Report
Title Note	Final rept.
NTIS Issue Number	199523