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Guidance Manual for the Integrated Exposure Uptake Biokinetic Model for Lead in Children.

PB93963510

Publication Date	1994
Page Count	258
Abstract	The Guidance Manual has been developed to assist the user in providing appropriate input to the Integrated Exposure Uptake Biokinetic (IEUBK) Model for Lead. The IEUBK Model is designed to model exposure from lead in air, water, soil, dust, diet, and paint and other sources with pharmacokinetic modeling to predict blood lead levels in children 6 months to 7 years old. The manual emphasizes the use of the IEUBK Model for estimating risks from childhood lead exposure to soil and household dust that might be encountered at CERCLA/RCRA sites, although other applications of the model are possible. The manual provides background information on environmental exposure parameters and recommends some useful approaches that allow flexibility for site-specific risk assessments, where possible.
Keywords	Lead(Metal) Children Environmental exposure Health hazards Land pollution Soil contamination Food chains Air pollution effects(Humans) Water pollution effects(Humans) Soils Dust Biokinetic models Risk assessment IEUBK(Integrated Exposure Uptake Biokinetic) IEUBK model Pharmacokinetics
Source Agency	Office of Emergency and Remedial Response
NTIS Subject Category	68G - Environmental Health & Safety 57U - Public Health & Industrial Medicine 57Y - Toxicology
Corporate Authors	Environmental Protection Agency, Washington, DC. Office of Emergency and Remedial Response.
Supplemental Notes	See also, PB94-501517.
Document Type	Technical Report
NTIS Issue Number	199414

Guidance Manual for the Integrated Exposure Uptake Biokinetic Model for Lead in Children.

Guidance Manual for the Integrated Exposure Uptake Biokinetic Model for Lead in Children.
PB93963510

Publication Date	1994
Page Count	258
Abstract	The Guidance Manual has been developed to assist the user in providing appropriate input to the Integrated Exposure Uptake Biokinetic (IEUBK) Model for Lead. The IEUBK Model is designed to model exposure from lead in air, water, soil, dust, diet, and paint and other sources with pharmacokinetic modeling to predict blood lead levels in children 6 months to 7 years old. The manual emphasizes the use of the IEUBK Model for estimating risks from childhood lead exposure to soil and household dust that might be encountered at CERCLA/RCRA sites, although other applications of the model are possible. The manual provides background information on environmental exposure parameters and recommends some useful approaches that allow flexibility for site-specific risk assessments, where possible.
Keywords	Lead(Metal) Children Environmental exposure Health hazards Land pollution Soil contamination Food chains Air pollution effects(Humans) Water pollution effects(Humans) Soils Dust Biokinetic models Risk assessment IEUBK(Integrated Exposure Uptake Biokinetic) IEUBK model Pharmacokinetics
Source Agency	Office of Emergency and Remedial Response
NTIS Subject Category	68G - Environmental Health & Safety 57U - Public Health & Industrial Medicine 57Y - Toxicology
Corporate Authors	Environmental Protection Agency, Washington, DC. Office of Emergency and Remedial Response.
Supplemental Notes	See also, PB94-501517.
Document Type	Technical Report
NTIS Issue Number	199414