Publication Date |
1984 |
Page Count |
222 |
Abstract |
Rat fetuses were examined for teratological endpoints. The fetuses had been exposed to N,N-diethyl-m-toluamide (134623) (mDET), diethylene-glycol-monomethyl-ether (111773) (diEGME), or ethylene-glycol-monomethyl-ether (109864) (EGME), or were unexposed controls. No significant skeletal or visceral abnormalities were noted in rats exposed to mDET as compared to control animals. Exposure to diEGME caused several skeletal malformations and variations; the most common occurred in the ribs and included fused and/or wavy ribs and rudimentary cervical ribs. Administration of 50mg/kg EGME resulted in a significant increase in the percent of fetuses with visceral abnormalities. |
Keywords |
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Source Agency |
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NTIS Subject Category |
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Corporate Authors |
Intox Labs., Inc., Redfield, AR.; National Inst. for Occupational Safety and Health, Cincinnati, OH. |
Supplemental Notes |
Sponsored by National Inst. for Occupational Safety and Health, Cincinnati, OH. |
Document Type |
Technical Report |
NTIS Issue Number |
199308 |
Contract Number |
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