National Technical Reports Library - NTRL

National Technical Reports Library

The National Technical Information Service acquires, indexes, abstracts, and archives the largest collection of U.S. government-sponsored technical reports in existence. The NTRL offers online, free and open access to these authenticated government technical reports. Technical reports and documents in its repository may be available online for free either from the issuing federal agency, the U.S. Government Publishing Office’s Federal Digital System website, or through search engines.




Details
Actions:
Download PDFDownload PDF
Download

NIOSH Comments to DOL on the Occupational Safety and Health Administration's Reopening of the Rulemaking Record for the Proposed Rule on Occupational Exposure to Cadmium by R. W. Niemeier, November 4, 1991.


PB92206127

Publication Date 1991
Page Count 6
Abstract The testimony concerns the reopening of the rulemaking record on cadmium (7440439) by OSHA in an effort to allow public comment on new toxicologic data regarding solubility, bioavailability, toxicity, carcinogenicity, and potency of cadmium-sulfide (1306236) relative to other cadmium compounds. NIOSH agrees that cadmium-sulfide has been shown to be tumorigenic in rats by intratracheal installation; that cadmium-sulfide is carcinogenic in rats following intraperitoneal injection; and that short term studies of cadmium-sulfide pulmonary bioavailability demonstrate that long term bioavailability exists for the compound, even though it is lower than the bioavailabilities for cadmium-oxide (1306190) and cadmium-sulfate (10124364). NIOSH agrees that further studies on the carcinogenicity and bioavailability of cadmium-sulfide are warranted, but that the data available at this time do not offer a clear basis for treating the compound differently than any other cadmium compound from a regulatory standpoint.
Keywords
  • Occupational safety and health
  • Cadmium
  • Industrial medicine
  • Toxic substances
  • Occupational exposure
  • Toxicity
  • Public opinion
  • Cadmium sulfide
  • Solubility
  • Carcinogens
  • Bioaccumulation
  • Laboratory animals
  • CAS 7440-43-9
  • CAS 1306-23-6
  • CAS 1306-19-0
  • CAS 10124-36-4
Source Agency
  • National Institute for Occupational Safety and Health
NTIS Subject Category
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
  • 44G - Environmental & Occupational Factors
Corporate Authors National Inst. for Occupational Safety and Health, Cincinnati, OH.
Document Type Technical Report
NTIS Issue Number 199220
NIOSH Comments to DOL on the Occupational Safety and Health Administration's Reopening of the Rulemaking Record for the Proposed Rule on Occupational Exposure to Cadmium by R. W. Niemeier, November 4, 1991.
NIOSH Comments to DOL on the Occupational Safety and Health Administration's Reopening of the Rulemaking Record for the Proposed Rule on Occupational Exposure to Cadmium by R. W. Niemeier, November 4, 1991.
PB92206127

  • Occupational safety and health
  • Cadmium
  • Industrial medicine
  • Toxic substances
  • Occupational exposure
  • Toxicity
  • Public opinion
  • Cadmium sulfide
  • Solubility
  • Carcinogens
  • Bioaccumulation
  • Laboratory animals
  • CAS 7440-43-9
  • CAS 1306-23-6
  • CAS 1306-19-0
  • CAS 10124-36-4
  • National Institute for Occupational Safety and Health
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
  • 44G - Environmental & Occupational Factors
Loading