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Relationship between Blood Lead and Blood Pressure.


PB92205889

Publication Date 1992
Personal Author Hertz-Picciotto, I.; Croft, J.
Page Count 44
Abstract Epidemiologic studies on blood lead (7439921) and blood pressure in the general population and in occupationally exposed populations were reviewed. Six large population based surveys were conducted in Great Britain, Canada, Denmark, and the United States. In the population based studies, a small increase in blood pressure was associated with increases in blood lead. Increases in blood lead levels below 12 micrograms/deciliter (microg/dl) to levels higher than 25 microg/dl were consistently accompanied by blood pressure increases in the range of 1.2 to 4 mmHg diastolic blood pressure and 1.4 to 8 mmHg systolic blood pressure. Occupational groups which have been studied due to their exposure to lead at the workplace include those in lead smelting, steel cutting, scrap metal recovery, battery manufacturing, lead pigment and lead soldered stained glass work, car repair, and police work. Although the results of the studies on occupational cohorts were mixed, they suggested a small positive association between blood lead and blood pressure. Methodologies used in the studies were critiqued. The authors recommend factors for future study.
Keywords
  • Blood pressure
  • Lead
  • Occupational exposure
  • Blood chemical analysis
  • Cohort studies
  • Metal industry
  • Epidemiology
  • Antihypertensive agents
  • Longitudinal studies
  • Atomic absorption spectrophotometry
  • CAS 7439-92-1
Source Agency
  • National Institute for Occupational Safety and Health
NTIS Subject Category
  • 57U - Public Health & Industrial Medicine
Corporate Authors North Carolina Univ. at Chapel Hill. Dept. of Epidemiology.; National Inst. for Occupational Safety and Health, Cincinnati, OH. Div.
Supplemental Notes Sponsored by National Inst. for Occupational Safety and Health, Cincinnati, OH. Div. of Standards Development and Technology Transfer.
Document Type Technical Report
NTIS Issue Number 199220
Relationship between Blood Lead and Blood Pressure.
Relationship between Blood Lead and Blood Pressure.
PB92205889

  • Blood pressure
  • Lead
  • Occupational exposure
  • Blood chemical analysis
  • Cohort studies
  • Metal industry
  • Epidemiology
  • Antihypertensive agents
  • Longitudinal studies
  • Atomic absorption spectrophotometry
  • CAS 7439-92-1
  • National Institute for Occupational Safety and Health
  • 57U - Public Health & Industrial Medicine
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