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Final Report on the Reproductive Toxicity of Tris(2-Chloroethyl)phosphate Reproduction and Fertility Assessment in Swiss CD-1 Mice When Administered via Gavage.

PB92129170

Publication Date	1991
Personal Author	Gulati, D. K.; Barnes, L. H.; Chapin, R. E.; Heindel, J.
Page Count	270
Abstract	Tris(2-chloroethyl)phosphate (TCEP) is one of the class of tris organophosphates. It is used as a flame-retardant for plastics and synthetic fibers. TCEP was tested for its effects on fertility and reproduction in Swiss CD-1 mice according to the Continuous Breeding Protocol. It was administered via gavage. Based on results of previous data and a dose-finding study, 175, 350, and 700 mg/kg bw were chosen to investigate effects on fertility and reproduction.
Keywords	Toxicity Reproduction(Biology) Fire resistant coatings Body weight Mice Dose-response relationships Litter size Tables(Data) Fertility Organ weight Kidney Water consumption Tris(2-chloroethyl)phosphate) CAS 115-96-8
Source Agency	National Institute of Environmental Health Sciences
NTIS Subject Category	57Y - Toxicology 57S - Physiology
Corporate Authors	Environmental Health Research and Testing, Inc., Lexington, KY.; National Toxicology Program, Research Triangle Park, NC.
Supplemental Notes	See also PB91-171728. Sponsored by National Toxicology Program, Research Triangle Park, NC.
Document Type	Technical Report
NTIS Issue Number	199207
Contract Number	NTP-NO1-ES-65142

Final Report on the Reproductive Toxicity of Tris(2-Chloroethyl)phosphate Reproduction and Fertility Assessment in Swiss CD-1 Mice When Administered via Gavage.

Final Report on the Reproductive Toxicity of Tris(2-Chloroethyl)phosphate Reproduction and Fertility Assessment in Swiss CD-1 Mice When Administered via Gavage.
PB92129170

Publication Date	1991
Personal Author	Gulati, D. K.; Barnes, L. H.; Chapin, R. E.; Heindel, J.
Page Count	270
Abstract	Tris(2-chloroethyl)phosphate (TCEP) is one of the class of tris organophosphates. It is used as a flame-retardant for plastics and synthetic fibers. TCEP was tested for its effects on fertility and reproduction in Swiss CD-1 mice according to the Continuous Breeding Protocol. It was administered via gavage. Based on results of previous data and a dose-finding study, 175, 350, and 700 mg/kg bw were chosen to investigate effects on fertility and reproduction.
Keywords	Toxicity Reproduction(Biology) Fire resistant coatings Body weight Mice Dose-response relationships Litter size Tables(Data) Fertility Organ weight Kidney Water consumption Tris(2-chloroethyl)phosphate) CAS 115-96-8
Source Agency	National Institute of Environmental Health Sciences
NTIS Subject Category	57Y - Toxicology 57S - Physiology
Corporate Authors	Environmental Health Research and Testing, Inc., Lexington, KY.; National Toxicology Program, Research Triangle Park, NC.
Supplemental Notes	See also PB91-171728. Sponsored by National Toxicology Program, Research Triangle Park, NC.
Document Type	Technical Report
NTIS Issue Number	199207
Contract Number	NTP-NO1-ES-65142