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Effects of 27 MHz Radiation on Somatic and Germ Cells.

PB92124007

Publication Date	1991
Personal Author	Cleary, S. F.
Page Count	12
Abstract	A study was made of the dose dependence of effects of 27 and 2450 megahertz (MHz) continuous wave (CW) and pulse modulated (PM) radiation exposure of normal resting peripheral human lymphocytes, human glioma (LN71), HeLa, and Chinese-hamster-ovary (CHO) cells. Direct radiation effects on mouse germ cells were also investigated. Effects of high frequency electromagnetic radiation (EMR) on lymphocyte and glioma mitogenesis and the CHO cell cycle in-vitro provide evidence of direct dose or dose rate dependent alteration of a highly physiologically significant cellular endpoint. Although in-vitro data cannot be extrapolated directly to in-vivo responses, the experimental conditions of these in-vitro studies suggest that qualitatively similar effects may be induced by in-vivo exposure to electromagnetic fields of these frequencies. The author concludes that physiologically significant cellular alterations are induced by 27 and 2450MHz CW and PM radiation exposure under conditions that do not involve heating. The author suggests that the adequacy of radiofrequency occupational exposure guidelines that suggest that health effects are attributable to radiation induced tissue heating must be questioned.
Keywords	Radiation dose-response relationship Germ cells Radiofrequency pulses Cell lines Cultured tumor cells Humans Mice Chinese hamsters Lymphocytes Glioma Ovary Liposomes
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57V - Radiobiology 57F - Cytology, Genetics, & Molecular Biology
Corporate Authors	Virginia Commonwealth Univ., Richmond. Dept. of Physiology.; National Inst. for Occupational Safety and Health, Atlanta, GA.
Supplemental Notes	Sponsored by National Inst. for Occupational Safety and Health, Atlanta, GA.
Document Type	Technical Report
Title Note	Rept. for 27 Sep 85-29 Sep 90.
NTIS Issue Number	199206

Effects of 27 MHz Radiation on Somatic and Germ Cells.

Effects of 27 MHz Radiation on Somatic and Germ Cells.
PB92124007

Publication Date	1991
Personal Author	Cleary, S. F.
Page Count	12
Abstract	A study was made of the dose dependence of effects of 27 and 2450 megahertz (MHz) continuous wave (CW) and pulse modulated (PM) radiation exposure of normal resting peripheral human lymphocytes, human glioma (LN71), HeLa, and Chinese-hamster-ovary (CHO) cells. Direct radiation effects on mouse germ cells were also investigated. Effects of high frequency electromagnetic radiation (EMR) on lymphocyte and glioma mitogenesis and the CHO cell cycle in-vitro provide evidence of direct dose or dose rate dependent alteration of a highly physiologically significant cellular endpoint. Although in-vitro data cannot be extrapolated directly to in-vivo responses, the experimental conditions of these in-vitro studies suggest that qualitatively similar effects may be induced by in-vivo exposure to electromagnetic fields of these frequencies. The author concludes that physiologically significant cellular alterations are induced by 27 and 2450MHz CW and PM radiation exposure under conditions that do not involve heating. The author suggests that the adequacy of radiofrequency occupational exposure guidelines that suggest that health effects are attributable to radiation induced tissue heating must be questioned.
Keywords	Radiation dose-response relationship Germ cells Radiofrequency pulses Cell lines Cultured tumor cells Humans Mice Chinese hamsters Lymphocytes Glioma Ovary Liposomes
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57V - Radiobiology 57F - Cytology, Genetics, & Molecular Biology
Corporate Authors	Virginia Commonwealth Univ., Richmond. Dept. of Physiology.; National Inst. for Occupational Safety and Health, Atlanta, GA.
Supplemental Notes	Sponsored by National Inst. for Occupational Safety and Health, Atlanta, GA.
Document Type	Technical Report
Title Note	Rept. for 27 Sep 85-29 Sep 90.
NTIS Issue Number	199206