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Hazard and Operability Study of an Ethylene Oxide Sterilizer for National Institute for Occupational Safety and Health.


PB90168980

Publication Date 1988
Page Count 80
Abstract A hazard and operability (HAZOP) study was conducted on a sterilizer supplied by compressed gas cylinders of ethylene-oxide (EtO). The sterilizer installation, equipment, and operational procedures were reviewed, and recommendations were developed both specifically for the studied installation and for the generic installation. The sterilizer consisted of a jacketed chamber and associated pumps, pipes, filters, valves and other equipment. Sterilizer facility design, sterilizer equipment design, leak monitoring, system utilities, equipment maintenance, and operational procedures were discussed. These recommendations should provide guidance to hospitals installing EtO sterilizers. The study also showed how the HAZOP study procedures which are typically used in large chemical facilities can be used on a small scale setting. The HAZOP study involved evaluating the facility as a series of systems. Log sheets of information gathered were included in the report. A process diagram of an EtO sterilizer was included along with a schematic of EtO piping from tanks to sterilizer, a schematic of EtO sample line, calibration gas line, and carrier gas line, and schematics of the air inlet line to chamber and the piping from EtO tank to supply valve.
Keywords
  • Medical equipment
  • Ethylene oxide
  • Sterilization
  • Hospitals
  • Tables(Data)
  • Graphs(Charts)
  • Exposure
  • Emission
  • Ventilation
  • Monitoring
  • Toxicity
  • Recommendations
  • Control equipment
  • Occupational exposure
  • Dose-response relationships
Source Agency
  • National Institute for Occupational Safety and Health
NTIS Subject Category
  • 44G - Environmental & Occupational Factors
  • 68A - Air Pollution & Control
  • 57Y - Toxicology
  • 57U - Public Health & Industrial Medicine
Corporate Authors National Inst. for Occupational Safety and Health, Cincinnati, OH.
Document Type Technical Report
Title Note Final rept.
NTIS Issue Number 199009
Hazard and Operability Study of an Ethylene Oxide Sterilizer for National Institute for Occupational Safety and Health.
Hazard and Operability Study of an Ethylene Oxide Sterilizer for National Institute for Occupational Safety and Health.
PB90168980

  • Medical equipment
  • Ethylene oxide
  • Sterilization
  • Hospitals
  • Tables(Data)
  • Graphs(Charts)
  • Exposure
  • Emission
  • Ventilation
  • Monitoring
  • Toxicity
  • Recommendations
  • Control equipment
  • Occupational exposure
  • Dose-response relationships
  • National Institute for Occupational Safety and Health
  • 44G - Environmental & Occupational Factors
  • 68A - Air Pollution & Control
  • 57Y - Toxicology
  • 57U - Public Health & Industrial Medicine
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