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Epidemiology of Asbestos Related Diseases.


PB90155904

Publication Date 1981
Personal Author Dement, J. M.
Page Count 50
Abstract Although there were several anecdotal reports from earlier times, the first well documented case of asbestosis was reported in 1906 in a worker engaged in the production of asbestos (1332214) textiles. In 1917 a report of ten cases of pulmonary fibrosis occurring at a Pennsylvania facility was published. The first detailed epidemiologic study of asbestos workers was undertaken in Great Britain in 1928. The first indication that asbestos might be a human carcinogen came in 1935 with the report of three independently diagnosed cases of lung cancer detected during autopsy of asbestos workers. Epidemiologic studies have now repeatedly demonstrated an association between asbestos exposure and increased mortality due to asbestosis, lung cancer, pleural and peritoneal mesothelioma, and gastrointestinal cancer. In some studies asbestos exposure has also been associated with increased risks for laryngeal cancer and cancer of the buccal cavity and pharynx. Studies which have been concerned with exposure to crocidolite (12001284), amosite (12172735), anthophyllite (17068789), tremolite (14567738), and chrysotile (12001295) were highlighted. Other topics reviewed included asbestos contamination of other minerals, the combined effects of asbestos exposure and tobacco smoke, mortality and pleural radiographic changes, and mixed fiber exposures.
Keywords
  • Industrial medicine
  • Asbestos
  • Epidemiology
  • Mortality
  • Asbestosis
  • Malignant neoplasms
  • Respiratory diseases
  • Exposure
  • Toxicity
  • Hazardous materials
  • Occupational diseases
  • Serpentine
  • Smoking
  • Toxic substances
  • Occupational safety and health
  • CAS 1332-21-4
  • CAS 12001-28-4
  • CAS 12172-73-5
  • CAS 17068-78-9
  • CAS 14567-73-8
  • CAS 12001-29-5
  • Risk assessment
Source Agency
  • National Institute for Occupational Safety and Health
NTIS Subject Category
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 41I - Job Environment
  • 68G - Environmental Health & Safety
  • 68A - Air Pollution & Control
Corporate Authors National Inst. for Occupational Safety and Health, Morgantown, WV. Div. of Respiratory Disease Studies.
Document Type Technical Report
NTIS Issue Number 199009
Epidemiology of Asbestos Related Diseases.
Epidemiology of Asbestos Related Diseases.
PB90155904

  • Industrial medicine
  • Asbestos
  • Epidemiology
  • Mortality
  • Asbestosis
  • Malignant neoplasms
  • Respiratory diseases
  • Exposure
  • Toxicity
  • Hazardous materials
  • Occupational diseases
  • Serpentine
  • Smoking
  • Toxic substances
  • Occupational safety and health
  • CAS 1332-21-4
  • CAS 12001-28-4
  • CAS 12172-73-5
  • CAS 17068-78-9
  • CAS 14567-73-8
  • CAS 12001-29-5
  • Risk assessment
  • National Institute for Occupational Safety and Health
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 41I - Job Environment
  • 68G - Environmental Health & Safety
  • 68A - Air Pollution & Control
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