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NIOSH (National Institute for Occupational Safety and Health) Testimony to the Subcommittee on the Environment, Committee on Commerce, United States Senate by Dr. Marcus M. Key on Wednesday, August 21, 1974.

PB89238026

Publication Date	1974
Page Count	10
Abstract	The testimony before the Subcommittee on the Environment reviewed the activities of the Department of Health, Education, and Welfare concerning health hazards associated with exposure to vinyl-chloride (75014) (VC). The speaker first reviewed the use of the monomer vinyl-chloride in the manufacturing of plastics and the production statistics. An occupational exposure limit of 500 parts per million (ppm), established in 1946, was lowered to 200 ppm on the demonstration of liver toxicity in animal studies. A renewed interest in the toxicity of the chemical occurred with the outbreak of acroosteolysis, a rare bone disease, among polyvinyl-chloride (PVC) reactor cleaners in the 1960s. The use of PVC bottles for distilled spirits was prohibited in 1973 when the results of tests indicated VC was leaching out of the bottles into the contents. A cluster of deaths from an unusual liver cancer within a 5-year period at one facility of the BF Goodrich's VC production company caused an extreme amount of concern and activity to pinpoint the causes and take the necessary steps to prevent further disease. Two of the outcomes of this intense study were the development of a liver angiosarcoma network by NIOSH and the Center for Diseases Control (CDC) and an epidemiologic study of workers exposed to VC as conducted by NIOSH and CDC.
Keywords	Environmental surveys Industrial medicine Vinyl chloride Hazards Exposure Toxicity Inspection Hazardous materials Plastics industry Epidemiology Research Liver neoplasms Risk Polymerization Carcinogens Toxic substances Occupational safety and health Testimony CAS 75-01-4
Source Agency	Centers for Disease Control Bureau of Laboratories National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 94D - Job Environment 41I - Job Environment 68G - Environmental Health & Safety 71O - Plastics
Corporate Authors	National Inst. for Occupational Safety and Health, Cincinnati, OH.
Document Type	Technical Report
NTIS Issue Number	198924

NIOSH (National Institute for Occupational Safety and Health) Testimony to the Subcommittee on the Environment, Committee on Commerce, United States Senate by Dr. Marcus M. Key on Wednesday, August 21, 1974.

NIOSH (National Institute for Occupational Safety and Health) Testimony to the Subcommittee on the Environment, Committee on Commerce, United States Senate by Dr. Marcus M. Key on Wednesday, August 21, 1974.
PB89238026

Publication Date	1974
Page Count	10
Abstract	The testimony before the Subcommittee on the Environment reviewed the activities of the Department of Health, Education, and Welfare concerning health hazards associated with exposure to vinyl-chloride (75014) (VC). The speaker first reviewed the use of the monomer vinyl-chloride in the manufacturing of plastics and the production statistics. An occupational exposure limit of 500 parts per million (ppm), established in 1946, was lowered to 200 ppm on the demonstration of liver toxicity in animal studies. A renewed interest in the toxicity of the chemical occurred with the outbreak of acroosteolysis, a rare bone disease, among polyvinyl-chloride (PVC) reactor cleaners in the 1960s. The use of PVC bottles for distilled spirits was prohibited in 1973 when the results of tests indicated VC was leaching out of the bottles into the contents. A cluster of deaths from an unusual liver cancer within a 5-year period at one facility of the BF Goodrich's VC production company caused an extreme amount of concern and activity to pinpoint the causes and take the necessary steps to prevent further disease. Two of the outcomes of this intense study were the development of a liver angiosarcoma network by NIOSH and the Center for Diseases Control (CDC) and an epidemiologic study of workers exposed to VC as conducted by NIOSH and CDC.
Keywords	Environmental surveys Industrial medicine Vinyl chloride Hazards Exposure Toxicity Inspection Hazardous materials Plastics industry Epidemiology Research Liver neoplasms Risk Polymerization Carcinogens Toxic substances Occupational safety and health Testimony CAS 75-01-4
Source Agency	Centers for Disease Control Bureau of Laboratories National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 94D - Job Environment 41I - Job Environment 68G - Environmental Health & Safety 71O - Plastics
Corporate Authors	National Inst. for Occupational Safety and Health, Cincinnati, OH.
Document Type	Technical Report
NTIS Issue Number	198924