| Abstract |
Information profiles are presented on the following compounds: 2-chlorophenol (95578), 3-chlorophenol (108430), 4-chlorophenol (106489), 2,4-dichlorophenol (120832), 2,5-dichlorophenol (583788), 2,6-dichlorophenol (87650), 2,3,6-trichlorophenol (933755), 2,4,5-trichlorophenol (95954), 2,4,6-trichlorophenol (88062). Studies indicate that, administered in acute lethal doses, the chlorophenols produce excitation and increased respiration followed by motor weakness, hypotonia, convulsions, coma and death. All chlorophenols are well absorbed dermally, and toxic to skin and eyes. Workers exposed to 4-chlorophenol have demonstrated signs of functional disorders of the central and peripheral nervous systems and mucous membrane structure. Testing in mice has produced increased incidences of hepatocellular carcinomas, adenomas, hepatomas, and reticulum cell sarcomas. |
