National Technical Reports Library - NTRL

National Technical Reports Library


Details
Actions:
Download PDFDownload XML
Download

Information Profiles on Potential Occupational Hazards: Aminoazobenzenes.


PB89215826

Publication Date 1981
Page Count 116
Abstract Information profiles were prepared for the following aminoazobenzenes: 4-aminoazobenzene (60093), 4-aminoazobenzene-3, 4'-disulfonic-acid (101508), 4-aminoazobenzene-3, 4'-disulfonic-acid-disodium-salt (2706287), 4-aminoazobenzene-hydrochloride (3457985), 4'-aminoazobenzene-4-sulfonic-acid (104234), 4'-aminoazobenzene-4-sulfonic-acid-sodium-salt (2491716), ortho-aminoazotoluene (97563), ortho-aminoazotoluene-hydrochloride (2298137), C.I.-Disperse-Orange-3 (730405), C.I.-Disperse-Red-1 (2872528), C.I.-Disperse-Red-5 (3769571), C.I.-Disperse-Red-17 (3179893), C.I.-Disperse-Yellow-3 (2832408), chrysodine (532821), 2,4-diaminoazobenzene (495545), and N,N,-diethylaminoazobenze (2481949). Information suggested that these compounds were only mildly toxic following acute exposure. Organ damage was noted in the liver, kidneys, and spleen following subchronic or chronic exposure. After metabolic activation in the Ames assay, positive findings were obtained for 4-aminoazobenzene, chrysodine and ortho-animoazotoluene. Aminoazobenzenes, 4-aminoazobenzenes, chrysodine and ortho-aminoazotoluene have tested positively in carcinogenicity studies using laboratory mice. Ortho-aminoazotoluene crossed the placenta and increased tumor incidence in the F1 generation.
Keywords
  • Industrial medicine
  • Exposure
  • Toxicity
  • Chemical analysis
  • Utilization
  • Production
  • Occupational safety and health
  • Toxic substances
  • Aminoazobenzenes
  • Biological effects
  • CAS 60-09-3
  • CAS 101-50-8
  • CAS 2706-28-7
  • CAS 3457-98-5
  • CAS 104-23-4
  • CAS 2491-71-6
  • CAS 97-56-3
  • CAS 2298-13-7
  • CAS 730-40-5
  • CAS 2875-52-8
  • CAS 3769-57-1
  • CAS 3179-89-3
  • CAS 2832-40-8
  • CAS 532-82-1
  • CAS 495-54-5
  • CAS 2481-94-9
Source Agency
  • National Institute for Occupational Safety and Health
NTIS Subject Category
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 41I - Job Environment
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
Corporate Authors Syracuse Research Corp., NY. Center for Chemical Hazard Assessment.; National Inst. for Occupational Safety and Health, Rockville, MD.
Supplemental Notes Sponsored by National Inst. for Occupational Safety and Health, Rockville, MD.
Document Type Technical Report
Title Note Draft rept. (Second).
NTIS Issue Number 198921
Contract Number
  • PHS-NIOSH-210-79-0030
Information Profiles on Potential Occupational Hazards: Aminoazobenzenes.
Information Profiles on Potential Occupational Hazards: Aminoazobenzenes.
PB89215826

  • Industrial medicine
  • Exposure
  • Toxicity
  • Chemical analysis
  • Utilization
  • Production
  • Occupational safety and health
  • Toxic substances
  • Aminoazobenzenes
  • Biological effects
  • CAS 60-09-3
  • CAS 101-50-8
  • CAS 2706-28-7
  • CAS 3457-98-5
  • CAS 104-23-4
  • CAS 2491-71-6
  • CAS 97-56-3
  • CAS 2298-13-7
  • CAS 730-40-5
  • CAS 2875-52-8
  • CAS 3769-57-1
  • CAS 3179-89-3
  • CAS 2832-40-8
  • CAS 532-82-1
  • CAS 495-54-5
  • CAS 2481-94-9
  • National Institute for Occupational Safety and Health
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 41I - Job Environment
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
  • PHS-NIOSH-210-79-0030
Loading