| Abstract |
The report reviews and evaluates recent literature concerning hazards associated with exposure to ethylene-dibromide (106934). Workers exposed to ethylene-dibromide may experience severe acute respiratory damage, central nervous system depression, and severe vomiting on inhalation of the vapors. Skin contact can cause erythema, blistering, and ulceration. A recommended ceiling level for occupational exposures has been set by NIOSH at 1 mg/m3. NIOSH has identified the following areas as needing future research: epidemiological surveys, liver and kidney function tests, and biological monitoring among exposed workers. It was also recommended that animal studies be conducted with regard to possible carcinogenic, mutagenic, and teratogenic effects. Other specific areas covered in the review included the results of animals studies already conducted in the areas of carcinogenicity, mutagenicity, reproductive effects, developmental effects, hepatic effects, metabolic studies, synergistic effects, general toxicity, work practices, engineering controls, sampling and analytical methods. |
