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Information Profiles on Potential Occupational Hazards: Nitroparaffins.

PB89215784

Publication Date	1981
Page Count	83
Abstract	Profiles of information are presented for the following nitroparaffins: nitroethane (79243), nitromethane (75525), l-nitropropane (108032), 2-nitropropane (79469), tetranitromethane (509148), and trinitromethane (517259). Oral and inhalation toxicities and the degree of histological damage increase with increasing molecular weight of the compounds. The primary effects include histological liver damage and central nervous system depression, both atactic and narcotic changes, regardless of the route of administration or the duration of exposure. Vapor exposures also cause respiratory tract and conjunctival irritation and pulmonary edema. Symptoms of exposure in humans include headache, nausea, damage to the respiratory tract and liver damage. Most of the exposures to nitroparaffins resulting from occupational pursuits have been to 2-nitropropane.
Keywords	Industrial medicine Nitro compounds Toxicity Exposure Control equipment Chemical analysis Utilization Production Occupational safety and health Toxic substances Nitroparaffins Biological effects CAS 79-24-3 CAS 75-52-5 CAS 108-03-2 CAS 79-46-9 CAS 509-14-8 CAS 517-25-9
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 41I - Job Environment 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	Syracuse Research Corp., NY. Center for Chemical Hazard Assessment.; National Inst. for Occupational Safety and Health, Rockville, MD.
Supplemental Notes	Sponsored by National Inst. for Occupational Safety and Health, Rockville, MD.
Document Type	Technical Report
Title Note	Draft rept. (Second).
NTIS Issue Number	198921
Contract Number	PHS-NIOSH-210-79-0030

Information Profiles on Potential Occupational Hazards: Nitroparaffins.

Information Profiles on Potential Occupational Hazards: Nitroparaffins.
PB89215784

Publication Date	1981
Page Count	83
Abstract	Profiles of information are presented for the following nitroparaffins: nitroethane (79243), nitromethane (75525), l-nitropropane (108032), 2-nitropropane (79469), tetranitromethane (509148), and trinitromethane (517259). Oral and inhalation toxicities and the degree of histological damage increase with increasing molecular weight of the compounds. The primary effects include histological liver damage and central nervous system depression, both atactic and narcotic changes, regardless of the route of administration or the duration of exposure. Vapor exposures also cause respiratory tract and conjunctival irritation and pulmonary edema. Symptoms of exposure in humans include headache, nausea, damage to the respiratory tract and liver damage. Most of the exposures to nitroparaffins resulting from occupational pursuits have been to 2-nitropropane.
Keywords	Industrial medicine Nitro compounds Toxicity Exposure Control equipment Chemical analysis Utilization Production Occupational safety and health Toxic substances Nitroparaffins Biological effects CAS 79-24-3 CAS 75-52-5 CAS 108-03-2 CAS 79-46-9 CAS 509-14-8 CAS 517-25-9
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 41I - Job Environment 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	Syracuse Research Corp., NY. Center for Chemical Hazard Assessment.; National Inst. for Occupational Safety and Health, Rockville, MD.
Supplemental Notes	Sponsored by National Inst. for Occupational Safety and Health, Rockville, MD.
Document Type	Technical Report
Title Note	Draft rept. (Second).
NTIS Issue Number	198921
Contract Number	PHS-NIOSH-210-79-0030