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Information Profiles on Potential Occupational Hazards: Nitroparaffins.


PB89215784

Publication Date 1981
Page Count 83
Abstract Profiles of information are presented for the following nitroparaffins: nitroethane (79243), nitromethane (75525), l-nitropropane (108032), 2-nitropropane (79469), tetranitromethane (509148), and trinitromethane (517259). Oral and inhalation toxicities and the degree of histological damage increase with increasing molecular weight of the compounds. The primary effects include histological liver damage and central nervous system depression, both atactic and narcotic changes, regardless of the route of administration or the duration of exposure. Vapor exposures also cause respiratory tract and conjunctival irritation and pulmonary edema. Symptoms of exposure in humans include headache, nausea, damage to the respiratory tract and liver damage. Most of the exposures to nitroparaffins resulting from occupational pursuits have been to 2-nitropropane.
Keywords
  • Industrial medicine
  • Nitro compounds
  • Toxicity
  • Exposure
  • Control equipment
  • Chemical analysis
  • Utilization
  • Production
  • Occupational safety and health
  • Toxic substances
  • Nitroparaffins
  • Biological effects
  • CAS 79-24-3
  • CAS 75-52-5
  • CAS 108-03-2
  • CAS 79-46-9
  • CAS 509-14-8
  • CAS 517-25-9
Source Agency
  • National Institute for Occupational Safety and Health
NTIS Subject Category
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 41I - Job Environment
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
Corporate Authors Syracuse Research Corp., NY. Center for Chemical Hazard Assessment.; National Inst. for Occupational Safety and Health, Rockville, MD.
Supplemental Notes Sponsored by National Inst. for Occupational Safety and Health, Rockville, MD.
Document Type Technical Report
Title Note Draft rept. (Second).
NTIS Issue Number 198921
Contract Number
  • PHS-NIOSH-210-79-0030
Information Profiles on Potential Occupational Hazards: Nitroparaffins.
Information Profiles on Potential Occupational Hazards: Nitroparaffins.
PB89215784

  • Industrial medicine
  • Nitro compounds
  • Toxicity
  • Exposure
  • Control equipment
  • Chemical analysis
  • Utilization
  • Production
  • Occupational safety and health
  • Toxic substances
  • Nitroparaffins
  • Biological effects
  • CAS 79-24-3
  • CAS 75-52-5
  • CAS 108-03-2
  • CAS 79-46-9
  • CAS 509-14-8
  • CAS 517-25-9
  • National Institute for Occupational Safety and Health
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 41I - Job Environment
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
  • PHS-NIOSH-210-79-0030
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