Publication Date |
1981 |
Page Count |
83 |
Abstract |
Profiles of information are presented for the following nitroparaffins: nitroethane (79243), nitromethane (75525), l-nitropropane (108032), 2-nitropropane (79469), tetranitromethane (509148), and trinitromethane (517259). Oral and inhalation toxicities and the degree of histological damage increase with increasing molecular weight of the compounds. The primary effects include histological liver damage and central nervous system depression, both atactic and narcotic changes, regardless of the route of administration or the duration of exposure. Vapor exposures also cause respiratory tract and conjunctival irritation and pulmonary edema. Symptoms of exposure in humans include headache, nausea, damage to the respiratory tract and liver damage. Most of the exposures to nitroparaffins resulting from occupational pursuits have been to 2-nitropropane. |
Keywords |
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Source Agency |
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NTIS Subject Category |
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Corporate Authors |
Syracuse Research Corp., NY. Center for Chemical Hazard Assessment.; National Inst. for Occupational Safety and Health, Rockville, MD. |
Supplemental Notes |
Sponsored by National Inst. for Occupational Safety and Health, Rockville, MD. |
Document Type |
Technical Report |
Title Note |
Draft rept. (Second). |
NTIS Issue Number |
198921 |
Contract Number |
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