| Abstract |
Information profiles are provided for the following glycols: 2-butene-1,4-diol (110645), 1,3-butylene-glycol (107880), 1,4-butylene-glycol (110634), 2-butyne-1,4-diol (110656), 1,4-cyclohexanedimethanol (105088), diethylene-glycol (111466), dipropylene-glycol (108612), ethylene-glycol (107211), 2-ethyl-1,3-hexanediol (94962), 1,6-hexanediol (629118), 2,5-hexanediol (2935446), 2-methyl-2-propyl-1,3-propanediol (78262), neopentyl-glycol (126307), 1,5-pentanediol (111295), propylene-glycol (57556), tetraethylene-glycol (112607), triethylene-glycol (112276), 2,2,4-trimethyl-1,3-pentanediol (144194), and tripropylene-glycol (1638160). The acute toxicity of these compounds was characterized by central nervous system depression. Some of the glycols have caused renal damage of varying degrees. Some of the glycols were readily absorbed through the skin. Administration of diethylene-glycol to animals has caused formation of bladder stones. Investigation of possible carcinogenic, teratogenic, reproductive, or mutagenic potentials for these compounds has been very limited. |
