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Information Profiles on Potential Occupational Hazards: Glycols.


PB89215776

Publication Date 1982
Page Count 214
Abstract Information profiles are provided for the following glycols: 2-butene-1,4-diol (110645), 1,3-butylene-glycol (107880), 1,4-butylene-glycol (110634), 2-butyne-1,4-diol (110656), 1,4-cyclohexanedimethanol (105088), diethylene-glycol (111466), dipropylene-glycol (108612), ethylene-glycol (107211), 2-ethyl-1,3-hexanediol (94962), 1,6-hexanediol (629118), 2,5-hexanediol (2935446), 2-methyl-2-propyl-1,3-propanediol (78262), neopentyl-glycol (126307), 1,5-pentanediol (111295), propylene-glycol (57556), tetraethylene-glycol (112607), triethylene-glycol (112276), 2,2,4-trimethyl-1,3-pentanediol (144194), and tripropylene-glycol (1638160). The acute toxicity of these compounds was characterized by central nervous system depression. Some of the glycols have caused renal damage of varying degrees. Some of the glycols were readily absorbed through the skin. Administration of diethylene-glycol to animals has caused formation of bladder stones. Investigation of possible carcinogenic, teratogenic, reproductive, or mutagenic potentials for these compounds has been very limited.
Keywords
  • Industrial medicine
  • Glycols
  • Exposure
  • Toxicity
  • Chemical analysis
  • Utilization
  • Production
  • Control equipment
  • Occupational safety and health
  • Toxic substances
  • CAS 1638-16-0
  • Biological effects
  • CAS 110-64-5
  • CAS 107-88-0
  • CAS 110-63-4
  • CAS 110-65-6
  • CAS 144-19-4
  • CAS 105-08-8
  • CAS 111-46-6
  • CAS 108-61-2
  • CAS 107-21-1
  • CAS 94-96-2
  • CAS 629-11-8
  • CAS 2935-44-6
  • CAS 78-26-2
  • CAS 126-30-7
  • CAS 111-29-5
  • CAS 57-55-6
  • CAS 112-60-7
  • CAS 112-27-6
Source Agency
  • National Institute for Occupational Safety and Health
NTIS Subject Category
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 41I - Job Environment
  • 68G - Environmental Health & Safety
Corporate Authors Syracuse Research Corp., NY. Center for Chemical Hazard Assessment.; National Inst. for Occupational Safety and Health, Rockville, MD.
Supplemental Notes Sponsored by National Inst. for Occupational Safety and Health, Rockville, MD.
Document Type Technical Report
Title Note Draft rept. (Second).
NTIS Issue Number 198922
Contract Number
  • PHS-NIOSH-210-79-0030
Information Profiles on Potential Occupational Hazards: Glycols.
Information Profiles on Potential Occupational Hazards: Glycols.
PB89215776

  • Industrial medicine
  • Glycols
  • Exposure
  • Toxicity
  • Chemical analysis
  • Utilization
  • Production
  • Control equipment
  • Occupational safety and health
  • Toxic substances
  • CAS 1638-16-0
  • Biological effects
  • CAS 110-64-5
  • CAS 107-88-0
  • CAS 110-63-4
  • CAS 110-65-6
  • CAS 144-19-4
  • CAS 105-08-8
  • CAS 111-46-6
  • CAS 108-61-2
  • CAS 107-21-1
  • CAS 94-96-2
  • CAS 629-11-8
  • CAS 2935-44-6
  • CAS 78-26-2
  • CAS 126-30-7
  • CAS 111-29-5
  • CAS 57-55-6
  • CAS 112-60-7
  • CAS 112-27-6
  • National Institute for Occupational Safety and Health
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 41I - Job Environment
  • 68G - Environmental Health & Safety
  • PHS-NIOSH-210-79-0030
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