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Toxicity Evaluation for Establishing IDLH Values.


PB87229498

Publication Date 1979
Personal Author Price, N. H.; Yates, W. G.; Allen, S. D.; Waters, S. W.
Page Count 256
Abstract Acute whole body inhalation toxicology from exposure to the industrial chemicals, 2-aminoethanol (141435), 2-(diethylamino)ethanol (100378), diisopropylamine (108189), ortho-toluidine (95534), para-anisidine (104949), ortho-anisidine (90040), Aroclor 1254 (11097691), phosgene (75445), stibine (7803523), and diazomethane (334883) was tested in groups of 10 rats and 10 guinea pigs. Experimental data collected from the animal exposures is presented for each chemical used and for the differing exposure concentrations. Observations used to verify the impairment of ability of the test animals to escape, animal deaths, irreversible histopathological lesions, and the differences between control and test animal organ and body weight are presented. Data for each compound are summarized by results of chemical analyses, the type of effect, and the differences between test and control animal weight data.
Keywords
  • Environmental surveys
  • Industrial medicine
  • Chemical industry
  • Toxicity
  • Exposure
  • Air pollution
  • Laboratory animals
  • Inspection
  • Hazardous materials
  • Contamination
  • Ethanolamine
  • Phosgene
  • Toxic substances
  • Occupational safety and health
  • 2-Aminoethanol
  • 2-(Diethylamino) ethanol)
  • Diisopropylamine
  • Ortho-toluidine
  • Para-anisidine
  • Araclor 1254
  • Ortho-anisidine
  • Stibine
  • Diazomethane
Source Agency
  • National Institute for Occupational Safety and Health
NTIS Subject Category
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
  • 68A - Air Pollution & Control
Corporate Authors Utah Univ. Research Inst., Salt Lake City. UBTL Div.; National Inst. for Occupational Safety and Health, Cincinnati, OH.
Supplemental Notes Sponsored by National Inst. for Occupational Safety and Health, Cincinnati, OH.
Document Type Technical Report
Title Note Final rept.
NTIS Issue Number 198724
Contract Number
  • PHS-NIOSH-210-77-0048
Toxicity Evaluation for Establishing IDLH Values.
Toxicity Evaluation for Establishing IDLH Values.
PB87229498

  • Environmental surveys
  • Industrial medicine
  • Chemical industry
  • Toxicity
  • Exposure
  • Air pollution
  • Laboratory animals
  • Inspection
  • Hazardous materials
  • Contamination
  • Ethanolamine
  • Phosgene
  • Toxic substances
  • Occupational safety and health
  • 2-Aminoethanol
  • 2-(Diethylamino) ethanol)
  • Diisopropylamine
  • Ortho-toluidine
  • Para-anisidine
  • Araclor 1254
  • Ortho-anisidine
  • Stibine
  • Diazomethane
  • National Institute for Occupational Safety and Health
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
  • 68A - Air Pollution & Control
  • PHS-NIOSH-210-77-0048
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