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Information Profiles on Potential Occupational Hazards: Carbonyl Fluoride. Second Draft.

PB87174330

Publication Date	1981
Page Count	17
Abstract	Information on potential occupational hazards from exposure to carbonyl-fluoride (353504) was reviewed. Topics discussed included chemical and physical properties, production, use, manufacturers and distributors, manufacturing processes, occupational exposure, and biological effects. Potential exposure to carbonyl-fluoride occurs as a result of the thermal decomposition of polytetrafluoroethylene (PTFE) in air. Effects of acute exposure in animal studies included extreme malaise and weakness which preceded death. Subchronic exposure studies with PTFE pyrolysis products revealed pathologic changes in the respiratory tracts and livers of exposed animals. Protein, glucose, ketones, and occult blood appeared in the urine following exposure. No information was available concerning chronic exposures, carcinogenicity, mutagenicity, teratogenicity, or reproductive effects.
Keywords	Environmental surveys Industrial medicine Exposure Toxicity Inspection Hazardous materials Carbonyl compounds Concentration(Composition) Toxic substances Occupational safety and health Carbonyl fluoride Health hazards Biological effects CAS 353-50-4
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	Syracuse Research Corp., NY. Center for Chemical Hazard Assessment.; National Inst. for Occupational Safety and Health, Rockville, MD.
Supplemental Notes	Sponsored by National Inst. for Occupational Safety and Health, Rockville, MD.
Document Type	Technical Report
NTIS Issue Number	198715
Contract Number	PHS-NIOSH-210-79-0030

Information Profiles on Potential Occupational Hazards: Carbonyl Fluoride. Second Draft.

Information Profiles on Potential Occupational Hazards: Carbonyl Fluoride. Second Draft.
PB87174330

Publication Date	1981
Page Count	17
Abstract	Information on potential occupational hazards from exposure to carbonyl-fluoride (353504) was reviewed. Topics discussed included chemical and physical properties, production, use, manufacturers and distributors, manufacturing processes, occupational exposure, and biological effects. Potential exposure to carbonyl-fluoride occurs as a result of the thermal decomposition of polytetrafluoroethylene (PTFE) in air. Effects of acute exposure in animal studies included extreme malaise and weakness which preceded death. Subchronic exposure studies with PTFE pyrolysis products revealed pathologic changes in the respiratory tracts and livers of exposed animals. Protein, glucose, ketones, and occult blood appeared in the urine following exposure. No information was available concerning chronic exposures, carcinogenicity, mutagenicity, teratogenicity, or reproductive effects.
Keywords	Environmental surveys Industrial medicine Exposure Toxicity Inspection Hazardous materials Carbonyl compounds Concentration(Composition) Toxic substances Occupational safety and health Carbonyl fluoride Health hazards Biological effects CAS 353-50-4
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	Syracuse Research Corp., NY. Center for Chemical Hazard Assessment.; National Inst. for Occupational Safety and Health, Rockville, MD.
Supplemental Notes	Sponsored by National Inst. for Occupational Safety and Health, Rockville, MD.
Document Type	Technical Report
NTIS Issue Number	198715
Contract Number	PHS-NIOSH-210-79-0030