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Health Hazard Evaluation Report HETA 80-035-1635, Bofors-Nobel/Lakeway Corporation, Muskegon, Michigan.

PB86205739

Publication Date	1985
Personal Author	Handke, J. L.; Lee, S. A.; Patnode, R.; Singal, M.
Page Count	28
Abstract	Environmental and breathing zone samples were analyzed for dichlorobenzidine (91941), oryzalin (19044883), and dinitrochlorobenzene (97007) at Bofors/Nobel/Lakeway Corporation (SIC-2865), Muskegon, Michigan in November, 1980, February, 1981, and August, 1982. The evaluation was requested by the union local to investigate dermatitis, possible reproductive effects, and reported bladder cancer cases among the employees. Thirty six workers were interviewed by questionnaire. Medical records were reviewed. Urine samples were obtained before and after cleanup operations and analyzed for dichlorobenzidine. Breathing zone oryzalin and dichlorobenzidine concentrations averaged 28 and 0.9 micrograms per cubic meter, respectively. Full shift skin exposures to dichlorobenzidine averaged 6.3 micrograms per 25 square centimeters. Dichlorobenzidine surface contamination was found in the pack/out locker room; no dinitrochlorobenzene was detected. No adverse reproductive effects were reported. Fifty three percent of workers with potential dinitrochlorobenzene exposure and 31 percent without exposure reported skin problems. Ten cases of bladder cancer, with a mean latency of 13.3 years, were documented. Before cleanup operations began, 68 percent of the exposed workers had detectable urinary dichlorobenzidine, after cleanup, this was reduced to 28 percent. The authors conclude that there is a hazard from dichlorobenzidine. Recommendations include improving housekeeping procedures and possibly modifying production procedures to reduce dinitrochlorobenzene exposure.
Keywords	Environmental surveys Industrial medicine Chemical industry Exposure Toxicity Inspection Hazardous materials Air pollution Aromatic hydrocarbons Toxic substances Occupational safety and health Indoor air pollution SIC 2865 EPA region 5 Benzidene/dichloro Benzene/chloro-dinitro Surflan
Source Agency	Centers for Disease Control Bureau of Laboratories National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety 68A - Air Pollution & Control
Corporate Authors	National Inst. for Occupational Safety and Health, Cincinnati, OH. Hazard Evaluations and Technical Assistance Branch.
Document Type	Technical Report
NTIS Issue Number	198618

Health Hazard Evaluation Report HETA 80-035-1635, Bofors-Nobel/Lakeway Corporation, Muskegon, Michigan.

Health Hazard Evaluation Report HETA 80-035-1635, Bofors-Nobel/Lakeway Corporation, Muskegon, Michigan.
PB86205739

Publication Date	1985
Personal Author	Handke, J. L.; Lee, S. A.; Patnode, R.; Singal, M.
Page Count	28
Abstract	Environmental and breathing zone samples were analyzed for dichlorobenzidine (91941), oryzalin (19044883), and dinitrochlorobenzene (97007) at Bofors/Nobel/Lakeway Corporation (SIC-2865), Muskegon, Michigan in November, 1980, February, 1981, and August, 1982. The evaluation was requested by the union local to investigate dermatitis, possible reproductive effects, and reported bladder cancer cases among the employees. Thirty six workers were interviewed by questionnaire. Medical records were reviewed. Urine samples were obtained before and after cleanup operations and analyzed for dichlorobenzidine. Breathing zone oryzalin and dichlorobenzidine concentrations averaged 28 and 0.9 micrograms per cubic meter, respectively. Full shift skin exposures to dichlorobenzidine averaged 6.3 micrograms per 25 square centimeters. Dichlorobenzidine surface contamination was found in the pack/out locker room; no dinitrochlorobenzene was detected. No adverse reproductive effects were reported. Fifty three percent of workers with potential dinitrochlorobenzene exposure and 31 percent without exposure reported skin problems. Ten cases of bladder cancer, with a mean latency of 13.3 years, were documented. Before cleanup operations began, 68 percent of the exposed workers had detectable urinary dichlorobenzidine, after cleanup, this was reduced to 28 percent. The authors conclude that there is a hazard from dichlorobenzidine. Recommendations include improving housekeeping procedures and possibly modifying production procedures to reduce dinitrochlorobenzene exposure.
Keywords	Environmental surveys Industrial medicine Chemical industry Exposure Toxicity Inspection Hazardous materials Air pollution Aromatic hydrocarbons Toxic substances Occupational safety and health Indoor air pollution SIC 2865 EPA region 5 Benzidene/dichloro Benzene/chloro-dinitro Surflan
Source Agency	Centers for Disease Control Bureau of Laboratories National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety 68A - Air Pollution & Control
Corporate Authors	National Inst. for Occupational Safety and Health, Cincinnati, OH. Hazard Evaluations and Technical Assistance Branch.
Document Type	Technical Report
NTIS Issue Number	198618