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Carcinogenic Potential of Condensed Pyrolysis Effluents from Iron Foundry Casting Operations. Volume 5.


PB85215218

Publication Date 1984
Personal Author Shellenberger, T. E.; Garner, F. M.; Plankenhorn, L. J.
Page Count 216
Abstract Data tabulations for a carcinogenesis bioassay of condensed effluents from iron foundry casting operations that used hamsters as the test species are presented. In that study, Syrian-golden-hamsters were administered effluents from shell sand, green sand, furan (110009) or urethane (51796) casting molds once a week for 18 weeks by intratracheal instillation. The concentrations were 5 or 10 milligrams (mg) effluent in 0.2 milliliter of distilled water, except for the effluents from the urethane mold, which were administered in amounts of 2.5 or 5.0mg. Benzo(a)pyrene (50328) plus ferric-oxide (1309371) and ferric-oxide alone were administered as positive controls. The animals were maintained until 98 percent mortality occurred or until week 103 in the case of females or week 117 in the case of males. None of the effluents were found to be carcinogenic at the concentrations used. The histopathological results for each individual animals were tabulated. A tumor inventory for each animal was also constructed.
Keywords
  • Carcinogens
  • Environmental surveys
  • Industrial medicine
  • Foundries
  • Casting
  • Iron and steel industry
  • Bioassay
  • Exposure
  • Toxicity
  • Inspection
  • Hazardous materials
  • Air pollution
  • Laboratory animals
  • Tables(Data)
  • Furans
  • Urethanes
  • Iron oxides
  • Pathology
  • Toxic substances
  • Occupational safety and health
  • Indoor air pollution
  • CAS 110-00-9
  • Green sand
  • Shell sand
  • Benzo(a)pyrene)
  • CAS 51-79-6
  • CAS 1309-37-1
  • CAS 50-32-8
Source Agency
  • National Institute for Occupational Safety and Health
NTIS Subject Category
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 41I - Job Environment
  • 68G - Environmental Health & Safety
  • 68A - Air Pollution & Control
Corporate Authors Borriston Labs., Inc., Temple Hills, MD.; National Inst. for Occupational Safety and Health, Cincinnati, OH. Div.
Supplemental Notes See also Volume 4, PB85-215200. Portions of this document are not fully legible.
Document Type Technical Report
Title Note Final rept.
NTIS Issue Number 198521
Contract Number
  • PHS-NIOSH-210-78-0033
Carcinogenic Potential of Condensed Pyrolysis Effluents from Iron Foundry Casting Operations. Volume 5.
Carcinogenic Potential of Condensed Pyrolysis Effluents from Iron Foundry Casting Operations. Volume 5.
PB85215218

  • Carcinogens
  • Environmental surveys
  • Industrial medicine
  • Foundries
  • Casting
  • Iron and steel industry
  • Bioassay
  • Exposure
  • Toxicity
  • Inspection
  • Hazardous materials
  • Air pollution
  • Laboratory animals
  • Tables(Data)
  • Furans
  • Urethanes
  • Iron oxides
  • Pathology
  • Toxic substances
  • Occupational safety and health
  • Indoor air pollution
  • CAS 110-00-9
  • Green sand
  • Shell sand
  • Benzo(a)pyrene)
  • CAS 51-79-6
  • CAS 1309-37-1
  • CAS 50-32-8
  • National Institute for Occupational Safety and Health
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 41I - Job Environment
  • 68G - Environmental Health & Safety
  • 68A - Air Pollution & Control
  • PHS-NIOSH-210-78-0033
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