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Carcinogenic Potential of Condensed Pyrolysis Effluents from Iron Foundry Casting Operations. Volume 5.

PB85215218

Publication Date	1984
Personal Author	Shellenberger, T. E.; Garner, F. M.; Plankenhorn, L. J.
Page Count	216
Abstract	Data tabulations for a carcinogenesis bioassay of condensed effluents from iron foundry casting operations that used hamsters as the test species are presented. In that study, Syrian-golden-hamsters were administered effluents from shell sand, green sand, furan (110009) or urethane (51796) casting molds once a week for 18 weeks by intratracheal instillation. The concentrations were 5 or 10 milligrams (mg) effluent in 0.2 milliliter of distilled water, except for the effluents from the urethane mold, which were administered in amounts of 2.5 or 5.0mg. Benzo(a)pyrene (50328) plus ferric-oxide (1309371) and ferric-oxide alone were administered as positive controls. The animals were maintained until 98 percent mortality occurred or until week 103 in the case of females or week 117 in the case of males. None of the effluents were found to be carcinogenic at the concentrations used. The histopathological results for each individual animals were tabulated. A tumor inventory for each animal was also constructed.
Keywords	Carcinogens Environmental surveys Industrial medicine Foundries Casting Iron and steel industry Bioassay Exposure Toxicity Inspection Hazardous materials Air pollution Laboratory animals Tables(Data) Furans Urethanes Iron oxides Pathology Toxic substances Occupational safety and health Indoor air pollution CAS 110-00-9 Green sand Shell sand Benzo(a)pyrene) CAS 51-79-6 CAS 1309-37-1 CAS 50-32-8
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 41I - Job Environment 68G - Environmental Health & Safety 68A - Air Pollution & Control
Corporate Authors	Borriston Labs., Inc., Temple Hills, MD.; National Inst. for Occupational Safety and Health, Cincinnati, OH. Div.
Supplemental Notes	See also Volume 4, PB85-215200. Portions of this document are not fully legible.
Document Type	Technical Report
Title Note	Final rept.
NTIS Issue Number	198521
Contract Number	PHS-NIOSH-210-78-0033

Carcinogenic Potential of Condensed Pyrolysis Effluents from Iron Foundry Casting Operations. Volume 5.

Carcinogenic Potential of Condensed Pyrolysis Effluents from Iron Foundry Casting Operations. Volume 5.
PB85215218

Publication Date	1984
Personal Author	Shellenberger, T. E.; Garner, F. M.; Plankenhorn, L. J.
Page Count	216
Abstract	Data tabulations for a carcinogenesis bioassay of condensed effluents from iron foundry casting operations that used hamsters as the test species are presented. In that study, Syrian-golden-hamsters were administered effluents from shell sand, green sand, furan (110009) or urethane (51796) casting molds once a week for 18 weeks by intratracheal instillation. The concentrations were 5 or 10 milligrams (mg) effluent in 0.2 milliliter of distilled water, except for the effluents from the urethane mold, which were administered in amounts of 2.5 or 5.0mg. Benzo(a)pyrene (50328) plus ferric-oxide (1309371) and ferric-oxide alone were administered as positive controls. The animals were maintained until 98 percent mortality occurred or until week 103 in the case of females or week 117 in the case of males. None of the effluents were found to be carcinogenic at the concentrations used. The histopathological results for each individual animals were tabulated. A tumor inventory for each animal was also constructed.
Keywords	Carcinogens Environmental surveys Industrial medicine Foundries Casting Iron and steel industry Bioassay Exposure Toxicity Inspection Hazardous materials Air pollution Laboratory animals Tables(Data) Furans Urethanes Iron oxides Pathology Toxic substances Occupational safety and health Indoor air pollution CAS 110-00-9 Green sand Shell sand Benzo(a)pyrene) CAS 51-79-6 CAS 1309-37-1 CAS 50-32-8
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 41I - Job Environment 68G - Environmental Health & Safety 68A - Air Pollution & Control
Corporate Authors	Borriston Labs., Inc., Temple Hills, MD.; National Inst. for Occupational Safety and Health, Cincinnati, OH. Div.
Supplemental Notes	See also Volume 4, PB85-215200. Portions of this document are not fully legible.
Document Type	Technical Report
Title Note	Final rept.
NTIS Issue Number	198521
Contract Number	PHS-NIOSH-210-78-0033