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Acute Toxicity Studies of Cesium and Rubidium Compounds.

PB85178341

Publication Date	1972
Personal Author	Johnson, G. T.; Lewis, T. R.; Perone, V. B.
Page Count	31
Abstract	Recent and projected industrial applications have markedly increased the usage of the hydroxides and iodides of cesium and rubidium. However, the acute toxicologic properties of cesium and rubidium have been investigated only on a very limited scale. It was deemed desirable, therefore, to assess the acute toxicity of these compounds. The single dose oral LD50, primary skin irritation index, degree of eye irritation, and skin allergic sensitization potential procedures were used. For purposes of compound administration by the various routes, all test materials were dissolved or suspended in deionized and distilled water. The concentrations used for the eye and primary skin irritation studies were the same as those used in industry. The concentrations used for the skin sensitization studies represented levels for obtaining potential allergic reactions without causing skin irritation.
Keywords	Environmental surveys Industrial medicine Exposure Toxicity Inspection Hazardous materials Dosage Laboratory animals Skin diseases Tables(Data) Eye diseases Toxic substances Occupational safety and health Cesium iodides Rubidium iodides Cesium hydroxides Rubidium hydroxides
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	National Inst. for Occupational Safety and Health, Cincinnati, OH.
Document Type	Technical Report
NTIS Issue Number	198514

Acute Toxicity Studies of Cesium and Rubidium Compounds.

Acute Toxicity Studies of Cesium and Rubidium Compounds.
PB85178341

Publication Date	1972
Personal Author	Johnson, G. T.; Lewis, T. R.; Perone, V. B.
Page Count	31
Abstract	Recent and projected industrial applications have markedly increased the usage of the hydroxides and iodides of cesium and rubidium. However, the acute toxicologic properties of cesium and rubidium have been investigated only on a very limited scale. It was deemed desirable, therefore, to assess the acute toxicity of these compounds. The single dose oral LD50, primary skin irritation index, degree of eye irritation, and skin allergic sensitization potential procedures were used. For purposes of compound administration by the various routes, all test materials were dissolved or suspended in deionized and distilled water. The concentrations used for the eye and primary skin irritation studies were the same as those used in industry. The concentrations used for the skin sensitization studies represented levels for obtaining potential allergic reactions without causing skin irritation.
Keywords	Environmental surveys Industrial medicine Exposure Toxicity Inspection Hazardous materials Dosage Laboratory animals Skin diseases Tables(Data) Eye diseases Toxic substances Occupational safety and health Cesium iodides Rubidium iodides Cesium hydroxides Rubidium hydroxides
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	National Inst. for Occupational Safety and Health, Cincinnati, OH.
Document Type	Technical Report
NTIS Issue Number	198514