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Mesothelioma in Relation to Asbestos.


PB84241603

Publication Date 1970
Personal Author Smith, W. E.
Page Count 22
Abstract The carcinogenicity of asbestos (1332214) was examined in LVGLAK-hamsters. Hamsters were given a single injection of 0.5 milliliter of a suspension of 1 of 23 preparations of asbestos or other minerals into the right pleural cavity. Animals were followed for 650 to 700 days after injection or until death. Necropsies were performed. Thoracic contents were examined microscopically and histologically. Presence or absence of pleural adhesions and their character, plaques, thrombi, or other pathologies were noted. Mesotheliomas were found after injection of soft chrysotile (12001295), harsh chrysotile, amosite (12172735), diatomaceous earth, crocidolite (12001284), anthophyllite (16829439), nickel (7440020) powder, and microquartz fibers.
Keywords
  • Environmental surveys
  • Industrial medicine
  • Asbestos
  • Carcinogens
  • Exposure
  • Toxicity
  • Inspection
  • Hazardous materials
  • Laboratory animals
  • Diatomaceous earth
  • Crocidolite
  • Anthophyllite
  • Nickel
  • Serpentine
  • Toxic substances
  • Occupational safety and health
  • CAS 1332-21-4
  • CAS 12001-29-5
  • CAS 12001-28-5
  • CAS 12172-73-5
  • CAS 12001-28-4
  • CAS 16829-43-9
  • CAS 7440-02-0
Source Agency
  • National Institute for Occupational Safety and Health
NTIS Subject Category
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
Corporate Authors Health Research Inst., Madison, NJ.; National Inst. for Occupational Safety and Health, Cincinnati, OH.
Document Type Technical Report
Title Note Progress rept.
NTIS Issue Number 198426
Mesothelioma in Relation to Asbestos.
Mesothelioma in Relation to Asbestos.
PB84241603

  • Environmental surveys
  • Industrial medicine
  • Asbestos
  • Carcinogens
  • Exposure
  • Toxicity
  • Inspection
  • Hazardous materials
  • Laboratory animals
  • Diatomaceous earth
  • Crocidolite
  • Anthophyllite
  • Nickel
  • Serpentine
  • Toxic substances
  • Occupational safety and health
  • CAS 1332-21-4
  • CAS 12001-29-5
  • CAS 12001-28-5
  • CAS 12172-73-5
  • CAS 12001-28-4
  • CAS 16829-43-9
  • CAS 7440-02-0
  • National Institute for Occupational Safety and Health
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
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