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Biologic Standards for the Industrial Worker by Breath Analysis; Trichloroethylene.

PB83175844

Publication Date	1974
Personal Author	Stewart, R. D.; Hake, C. L.; LeBrun, A. J.; Peterson, J. E.; Forester, H. V.
Page Count	112
Abstract	This three-part report confirms the efficacy of the breath analysis technique for monitoring trichloroethylene (TCE) exposures, compares it to the urinary metabolites measurement method, and describes 'degreaser's flush,' the dermal response to using TCE while drinking alcoholic beverages. The first two sections describe the two monitoring techniques and compare results of their application in similar experiments on volunteers exposed to TCE vapor. The breath analysis technique is favored because of the speed and simplicity of sample collection, its unequivocal diagnosis of exposure, and its superiority in estimating the magnitude of recent exposure. The third section of the report covers an experiment in which ethanol was administered to volunteers who were repeatedly exposed to TCE vapor to elicit 'degreaser's flush.' Although the responsible mechanism is unknown, the two factors necessary for this dermal response appeared to be repeated exposure to TCE and the ingestion of an alcoholic beverage.
Keywords	Environmental surveys Industrial medicine Monitors Standards Exposure Toxicity Inspection Hazardous materials Chlorine organic compounds Degreasing Ethylene/trichloro Toxic substances Occupational safety and health
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	Medical Coll. of Wisconsin, Inc., Milwaukee.; National Inst. for Occupational Safety and Health, Cincinnati, OH. Div.
Supplemental Notes	Color illustrations reproduced in black and white.
Document Type	Technical Report
NTIS Issue Number	198316
Contract Number	PHS-HSM-99-72-0082

Biologic Standards for the Industrial Worker by Breath Analysis; Trichloroethylene.

Biologic Standards for the Industrial Worker by Breath Analysis; Trichloroethylene.
PB83175844

Publication Date	1974
Personal Author	Stewart, R. D.; Hake, C. L.; LeBrun, A. J.; Peterson, J. E.; Forester, H. V.
Page Count	112
Abstract	This three-part report confirms the efficacy of the breath analysis technique for monitoring trichloroethylene (TCE) exposures, compares it to the urinary metabolites measurement method, and describes 'degreaser's flush,' the dermal response to using TCE while drinking alcoholic beverages. The first two sections describe the two monitoring techniques and compare results of their application in similar experiments on volunteers exposed to TCE vapor. The breath analysis technique is favored because of the speed and simplicity of sample collection, its unequivocal diagnosis of exposure, and its superiority in estimating the magnitude of recent exposure. The third section of the report covers an experiment in which ethanol was administered to volunteers who were repeatedly exposed to TCE vapor to elicit 'degreaser's flush.' Although the responsible mechanism is unknown, the two factors necessary for this dermal response appeared to be repeated exposure to TCE and the ingestion of an alcoholic beverage.
Keywords	Environmental surveys Industrial medicine Monitors Standards Exposure Toxicity Inspection Hazardous materials Chlorine organic compounds Degreasing Ethylene/trichloro Toxic substances Occupational safety and health
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	Medical Coll. of Wisconsin, Inc., Milwaukee.; National Inst. for Occupational Safety and Health, Cincinnati, OH. Div.
Supplemental Notes	Color illustrations reproduced in black and white.
Document Type	Technical Report
NTIS Issue Number	198316
Contract Number	PHS-HSM-99-72-0082