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Biologic Standards for the Industrial Worker by Breath Analysis; Trichloroethylene.


PB83175844

Publication Date 1974
Personal Author Stewart, R. D.; Hake, C. L.; LeBrun, A. J.; Peterson, J. E.; Forester, H. V.
Page Count 112
Abstract This three-part report confirms the efficacy of the breath analysis technique for monitoring trichloroethylene (TCE) exposures, compares it to the urinary metabolites measurement method, and describes 'degreaser's flush,' the dermal response to using TCE while drinking alcoholic beverages. The first two sections describe the two monitoring techniques and compare results of their application in similar experiments on volunteers exposed to TCE vapor. The breath analysis technique is favored because of the speed and simplicity of sample collection, its unequivocal diagnosis of exposure, and its superiority in estimating the magnitude of recent exposure. The third section of the report covers an experiment in which ethanol was administered to volunteers who were repeatedly exposed to TCE vapor to elicit 'degreaser's flush.' Although the responsible mechanism is unknown, the two factors necessary for this dermal response appeared to be repeated exposure to TCE and the ingestion of an alcoholic beverage.
Keywords
  • Environmental surveys
  • Industrial medicine
  • Monitors
  • Standards
  • Exposure
  • Toxicity
  • Inspection
  • Hazardous materials
  • Chlorine organic compounds
  • Degreasing
  • Ethylene/trichloro
  • Toxic substances
  • Occupational safety and health
Source Agency
  • National Institute for Occupational Safety and Health
NTIS Subject Category
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
Corporate Authors Medical Coll. of Wisconsin, Inc., Milwaukee.; National Inst. for Occupational Safety and Health, Cincinnati, OH. Div.
Supplemental Notes Color illustrations reproduced in black and white.
Document Type Technical Report
NTIS Issue Number 198316
Contract Number
  • PHS-HSM-99-72-0082
Biologic Standards for the Industrial Worker by Breath Analysis; Trichloroethylene.
Biologic Standards for the Industrial Worker by Breath Analysis; Trichloroethylene.
PB83175844

  • Environmental surveys
  • Industrial medicine
  • Monitors
  • Standards
  • Exposure
  • Toxicity
  • Inspection
  • Hazardous materials
  • Chlorine organic compounds
  • Degreasing
  • Ethylene/trichloro
  • Toxic substances
  • Occupational safety and health
  • National Institute for Occupational Safety and Health
  • 57U - Public Health & Industrial Medicine
  • 57Y - Toxicology
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
  • PHS-HSM-99-72-0082
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