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Criteria for a Recommended Standard: Occupational Exposure to Glycidyl Ethers.

PB81229700

Publication Date	1978
Personal Author	Woodbury, C.
Page Count	208
Abstract	Glycidyl ethers are characterized by the presence of a three-carbon chain with an epoxide group and an ether linkage. This recommended standard applies to monoglycidyl ethers and diglycidyl ethers that contain an alkyl group, an aromatic group, or a moiety of the structure -(RO)n-R'. It does not include any halogenated compounds or polymerized forms. Most of the glycidyl ethers are liquids but some are solids. The most common use of these compounds is as reactive diluents in epoxy resins. Toxicologic data concerning these compounds are scarce, but those available show that glycidyl ethers are primary skin and eye irritants and that they are potential skin sensitizing agents. Some data suggest that di(2,3-epoxypropyl) ether should be regarded as a potential occupational carcinogogen and that n-butyl glycidyl ether is a mammalian mutagen. Some glycidyl ethers have also produced cytotoxic effects in animals.
Keywords	Hazardous materials Industrial medicine Environmental surveys Exposure Toxicity Criteria Inspection Standards Recommendations Industrial hygiene Concentration(Composition) Thresholds(Physiology) Oxygen organic compounds Ether/glycidyl Toxic substances Occupational safety and health Air sampling Maximum permissible exposures Mutagenesis Teratogenesis
Source Agency	Centers for Disease Control Bureau of Laboratories National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	SRI International, Menlo Park, CA.; National Inst. for Occupational Safety and Health, Rockville, MD.
Document Type	Technical Report
NTIS Issue Number	198123
Contract Number	PHS-CDC-99-74-31

Criteria for a Recommended Standard: Occupational Exposure to Glycidyl Ethers.

Criteria for a Recommended Standard: Occupational Exposure to Glycidyl Ethers.
PB81229700

Publication Date	1978
Personal Author	Woodbury, C.
Page Count	208
Abstract	Glycidyl ethers are characterized by the presence of a three-carbon chain with an epoxide group and an ether linkage. This recommended standard applies to monoglycidyl ethers and diglycidyl ethers that contain an alkyl group, an aromatic group, or a moiety of the structure -(RO)n-R'. It does not include any halogenated compounds or polymerized forms. Most of the glycidyl ethers are liquids but some are solids. The most common use of these compounds is as reactive diluents in epoxy resins. Toxicologic data concerning these compounds are scarce, but those available show that glycidyl ethers are primary skin and eye irritants and that they are potential skin sensitizing agents. Some data suggest that di(2,3-epoxypropyl) ether should be regarded as a potential occupational carcinogogen and that n-butyl glycidyl ether is a mammalian mutagen. Some glycidyl ethers have also produced cytotoxic effects in animals.
Keywords	Hazardous materials Industrial medicine Environmental surveys Exposure Toxicity Criteria Inspection Standards Recommendations Industrial hygiene Concentration(Composition) Thresholds(Physiology) Oxygen organic compounds Ether/glycidyl Toxic substances Occupational safety and health Air sampling Maximum permissible exposures Mutagenesis Teratogenesis
Source Agency	Centers for Disease Control Bureau of Laboratories National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	SRI International, Menlo Park, CA.; National Inst. for Occupational Safety and Health, Rockville, MD.
Document Type	Technical Report
NTIS Issue Number	198123
Contract Number	PHS-CDC-99-74-31