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An Analysis of Maximal Expiratory Flow-Volume Curves Based on an Analytical Model of Lung Mechanics.

PB81225971

Publication Date	1976
Personal Author	Hyatt, R. E.; Wilson, T. A.
Page Count	17
Abstract	Maximal expiratory flow-volume (FV) curves were analyzed using a mathematical model of lung mechanics. In the lung model, the parenchyma contained an array of membranes, and geometrical properties were derived from morphological data. The elastic properties were deduced by requiring the bulk expansion of the array to match the average pressure volume curve for the lung. Nonuniform deformations were analyzed. Performance of the model was tested by altering viscous flow losses, airway mechanisms and the viscoelastic and plastoelastic effects of lung tissue. Plateaus on isovolume pressure flow and FV curves based on lung pressure-volume were predicted and normal maximal flow ranges were established. The authors note the success and achievements of the model and its drawbacks. The analytical model is capable of predicting thoracic cavity and lung interaction related to ventilation and pleural pressure gradients.
Keywords	Lung function tests Mathematical models Data collection Elastic properties Assessments Viscosity Air flow
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57S - Physiology
Corporate Authors	Mayo Foundation, Rochester, MN.; Health Services and Mental Health Administration, Rockville, MD.
Document Type	Technical Report
Title Note	Contract rept.
NTIS Issue Number	198123
Contract Number	PHS-HSM-99-72-133

An Analysis of Maximal Expiratory Flow-Volume Curves Based on an Analytical Model of Lung Mechanics.

An Analysis of Maximal Expiratory Flow-Volume Curves Based on an Analytical Model of Lung Mechanics.
PB81225971

Publication Date	1976
Personal Author	Hyatt, R. E.; Wilson, T. A.
Page Count	17
Abstract	Maximal expiratory flow-volume (FV) curves were analyzed using a mathematical model of lung mechanics. In the lung model, the parenchyma contained an array of membranes, and geometrical properties were derived from morphological data. The elastic properties were deduced by requiring the bulk expansion of the array to match the average pressure volume curve for the lung. Nonuniform deformations were analyzed. Performance of the model was tested by altering viscous flow losses, airway mechanisms and the viscoelastic and plastoelastic effects of lung tissue. Plateaus on isovolume pressure flow and FV curves based on lung pressure-volume were predicted and normal maximal flow ranges were established. The authors note the success and achievements of the model and its drawbacks. The analytical model is capable of predicting thoracic cavity and lung interaction related to ventilation and pleural pressure gradients.
Keywords	Lung function tests Mathematical models Data collection Elastic properties Assessments Viscosity Air flow
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57S - Physiology
Corporate Authors	Mayo Foundation, Rochester, MN.; Health Services and Mental Health Administration, Rockville, MD.
Document Type	Technical Report
Title Note	Contract rept.
NTIS Issue Number	198123
Contract Number	PHS-HSM-99-72-133