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Carcinogenicity and Metabolism of Azo Dyes, Especially Those Derived from Benzidine.

PB81171027

Publication Date	1980
Personal Author	Boeniger, M.
Page Count	156
Abstract	Studies on the sites of carcinogenic action of benzidine (92875) in man and experimental animals, benzidine metabolism, azo compounds metabolism, and the epidemiological experience of industries using azo dyestuffs are reviewed. Industrial hygiene surveys to monitor the environment of workers exposed to azo dyes, monitor urinary excretions of aromatic amines and benzidine of those workers, and evaluate the effects of exposure to and the metabolism of azo dyes are described. The author concludes that benzidine derived dyes are potential carcinogens and recommends that other safe dyes be substituted for these dyes when possible.
Keywords	Azo dyes Industrial medicine Hazardous materials Epidemiology Aromatic hydrocarbons Metabolism Medical examination Laboratory animals Exposure Carcinogens Benzidines Toxic substances Occupational safety and health CAS-92-87-5 Carcinogenesis
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	National Inst. for Occupational Safety and Health, Cincinnati, OH.
Document Type	Technical Report
Title Note	Technical rept.
NTIS Issue Number	198114

Carcinogenicity and Metabolism of Azo Dyes, Especially Those Derived from Benzidine.

Carcinogenicity and Metabolism of Azo Dyes, Especially Those Derived from Benzidine.
PB81171027

Publication Date	1980
Personal Author	Boeniger, M.
Page Count	156
Abstract	Studies on the sites of carcinogenic action of benzidine (92875) in man and experimental animals, benzidine metabolism, azo compounds metabolism, and the epidemiological experience of industries using azo dyestuffs are reviewed. Industrial hygiene surveys to monitor the environment of workers exposed to azo dyes, monitor urinary excretions of aromatic amines and benzidine of those workers, and evaluate the effects of exposure to and the metabolism of azo dyes are described. The author concludes that benzidine derived dyes are potential carcinogens and recommends that other safe dyes be substituted for these dyes when possible.
Keywords	Azo dyes Industrial medicine Hazardous materials Epidemiology Aromatic hydrocarbons Metabolism Medical examination Laboratory animals Exposure Carcinogens Benzidines Toxic substances Occupational safety and health CAS-92-87-5 Carcinogenesis
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	National Inst. for Occupational Safety and Health, Cincinnati, OH.
Document Type	Technical Report
Title Note	Technical rept.
NTIS Issue Number	198114