National Technical Reports Library

The National Technical Information Service acquires, indexes, abstracts, and archives the largest collection of U.S. government-sponsored technical reports in existence. The NTRL offers online, free and open access to these authenticated government technical reports. Technical reports and documents in its repository may be available online for free either from the issuing federal agency, the U.S. Government Publishing Office’s Federal Digital System website, or through search engines.

Details

Mutagenicity Evaluation of FDA 75-88 Niacin (Nicotinic Acid).

PB278472

Publication Date	1977
Page Count	49
Abstract	The objective of this study was to evaluate niacin (nicotinic acid) for genetic activity in microbial assays with and without the addition of mammalian metabolic activation preparations.
Keywords	Food additives Genetics Nicotinic acid Mutations Microorganisms Bacteria Yeasts In vitro analysis Assaying Indicator species Evaluation Toxicity Dosage Tables(Data) Salmonella Vitamin B complex GRAS food ingredients Mutagenesis Generally recognized as safe food ingredients Saccharomyces cerevisiae Salmonella typhimurium Ames mutagenic assay system
Source Agency	Center for Food Safety and Applied Nutrition
NTIS Subject Category	98H - Food Technology 57F - Cytology, Genetics, & Molecular Biology
Corporate Authors	Litton Bionetics, Inc., Kensington, MD.; Food and Drug Administration, Washington, D.C. Bureau of Foods.
Document Type	Technical Report
Title Note	Final rept.
NTIS Issue Number	197813
Contract Number	FDA-223-76-2104

Mutagenicity Evaluation of FDA 75-88 Niacin (Nicotinic Acid).

Mutagenicity Evaluation of FDA 75-88 Niacin (Nicotinic Acid).
PB278472

Publication Date	1977
Page Count	49
Abstract	The objective of this study was to evaluate niacin (nicotinic acid) for genetic activity in microbial assays with and without the addition of mammalian metabolic activation preparations.
Keywords	Food additives Genetics Nicotinic acid Mutations Microorganisms Bacteria Yeasts In vitro analysis Assaying Indicator species Evaluation Toxicity Dosage Tables(Data) Salmonella Vitamin B complex GRAS food ingredients Mutagenesis Generally recognized as safe food ingredients Saccharomyces cerevisiae Salmonella typhimurium Ames mutagenic assay system
Source Agency	Center for Food Safety and Applied Nutrition
NTIS Subject Category	98H - Food Technology 57F - Cytology, Genetics, & Molecular Biology
Corporate Authors	Litton Bionetics, Inc., Kensington, MD.; Food and Drug Administration, Washington, D.C. Bureau of Foods.
Document Type	Technical Report
Title Note	Final rept.
NTIS Issue Number	197813
Contract Number	FDA-223-76-2104