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A Behavioral and Neurological Evaluation of Dry Cleaners Exposed to Perchloroethylene.

PB274794

Publication Date	1966
Personal Author	Tuttle, T. C.; Wood, G. D.; Crether, C. B.; Johnson, B. L.; Xintaras, C.
Page Count	92
Abstract	The adverse effects of perchloroethylene (PCE) on workers' neurologic and behavioral performance were examined in 27 volunteers who worked in various dry cleaning jobs, including 18 who were exposed daily to a mean 8-hour time-weighed average (TWA) exposure of 18 ppm; 8 of the 18 had a mean TWA exposure of 32 ppm. Neurological examination showed a significant difference between neurological ratings for exposed workers versus controls, but multiple regression analyses suggest the neurological deficits to be related to prior exposure to Stoddard's solvent, not PCE. The effects of acute PCE exposure were examined by giving workers behavioral performance tests both prior to work and following work. Although significant differences were recorded in performance of some perception and psychomotor tests, multiple regression analysis showed the post-shift performance decrements to be correlated with fatigue, not with PCE exposure. In summary, no evidence was found of deleterious effects of PCE on workers' neurologic health or behavioral performance. However, findings strongly suggest the involvement of Stoddard's solvent as a factor accounting for an increased incidence of abnormally large neurologic scores.
Keywords	Hazardous materials Industrial medicine Dry cleaning Solvents Naphthas Neurology Toxicology Behavior disorders Industrial hygiene Nervous system disorders Industrial atmospheres Air pollution Exposure Tables(Data) Recommendations Performance(Human) Medical examination Physiological effects Tests Standards Concentration(Composition) Ethylene/tetrachloro Toxic substances Occupational safety and health Behavioral toxicology Environmental health Threshold limit values Air sampling Neurotoxicity Maximum permissible exposure level
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety 92B - Psychology
Corporate Authors	Westinghouse Behavioral Services Center, Columbia, MD.; National Inst. for Occupational Safety and Health, Cincinnati, Ohio. Div.
Document Type	Technical Report
NTIS Issue Number	197805
Contract Number	PHS-HSM-99-73-35

A Behavioral and Neurological Evaluation of Dry Cleaners Exposed to Perchloroethylene.

A Behavioral and Neurological Evaluation of Dry Cleaners Exposed to Perchloroethylene.
PB274794

Publication Date	1966
Personal Author	Tuttle, T. C.; Wood, G. D.; Crether, C. B.; Johnson, B. L.; Xintaras, C.
Page Count	92
Abstract	The adverse effects of perchloroethylene (PCE) on workers' neurologic and behavioral performance were examined in 27 volunteers who worked in various dry cleaning jobs, including 18 who were exposed daily to a mean 8-hour time-weighed average (TWA) exposure of 18 ppm; 8 of the 18 had a mean TWA exposure of 32 ppm. Neurological examination showed a significant difference between neurological ratings for exposed workers versus controls, but multiple regression analyses suggest the neurological deficits to be related to prior exposure to Stoddard's solvent, not PCE. The effects of acute PCE exposure were examined by giving workers behavioral performance tests both prior to work and following work. Although significant differences were recorded in performance of some perception and psychomotor tests, multiple regression analysis showed the post-shift performance decrements to be correlated with fatigue, not with PCE exposure. In summary, no evidence was found of deleterious effects of PCE on workers' neurologic health or behavioral performance. However, findings strongly suggest the involvement of Stoddard's solvent as a factor accounting for an increased incidence of abnormally large neurologic scores.
Keywords	Hazardous materials Industrial medicine Dry cleaning Solvents Naphthas Neurology Toxicology Behavior disorders Industrial hygiene Nervous system disorders Industrial atmospheres Air pollution Exposure Tables(Data) Recommendations Performance(Human) Medical examination Physiological effects Tests Standards Concentration(Composition) Ethylene/tetrachloro Toxic substances Occupational safety and health Behavioral toxicology Environmental health Threshold limit values Air sampling Neurotoxicity Maximum permissible exposure level
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 57Y - Toxicology 94D - Job Environment 68G - Environmental Health & Safety 92B - Psychology
Corporate Authors	Westinghouse Behavioral Services Center, Columbia, MD.; National Inst. for Occupational Safety and Health, Cincinnati, Ohio. Div.
Document Type	Technical Report
NTIS Issue Number	197805
Contract Number	PHS-HSM-99-73-35