National Technical Reports Library

The National Technical Information Service acquires, indexes, abstracts, and archives the largest collection of U.S. government-sponsored technical reports in existence. The NTRL offers online, free and open access to these authenticated government technical reports. Technical reports and documents in its repository may be available online for free either from the issuing federal agency, the U.S. Government Publishing Office’s Federal Digital System website, or through search engines.

Details

Behavioral and Neurological Effects of Methyl Chloride.

PB274770

Publication Date	1976
Personal Author	Repko, J. D.; Jones, P. D.; Garcia, L. S.; Schneider, E. J.; Roseman, E.
Page Count	220
Abstract	Behavioral and neurological effects on workers exposed to methyl chloride were evaluated in 122 workers occupationally exposed to methyl chloride at 6 manufacturing plants using the solvent in fabricating processes. The duration of exposure correlated with airborne methyl chloride, with methyl chloride on the breath, and with blood hematocrit. Methyl chloride in the breath also related to airborne methyl chloride levels, while airborne methyl chloride and urine acidity correlated with hematocrit. Methyl chloride levels in ambient air and urine acidity were the two best indicators of workers' performance on behavioral tasks. No significant differences in the presence of abnormal neurological symptoms were noted between experimental and control groups. No significant differences were noted between exposed and non-exposed groups with respect to the presence of dysrhythmia. Methyl chloride adversely affected performance on cognitive time-sharing tasks and increased finger tremor. No relation was noted between exposure and psychological or personality tests.
Keywords	Organic solvents Chloromethanes Industrial medicine Toxicology Neurology Industrial atmospheres Air pollution Exposure Diagnosis Nervous system disorders Behavior disorders Performance(Human) Toxicity Hematology Blood chemical analysis Electroencephalography Behavioral toxicology Occupational safety and health Toxic substances Urinalysis
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57Y - Toxicology 57U - Public Health & Industrial Medicine 92B - Psychology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	Louisville Univ., KY. Performance Research Lab.; National Inst. for Occupational Safety and Health, Cincinnati, Ohio. Div.
Document Type	Technical Report
Title Note	Technical information rept.
NTIS Issue Number	197805
Contract Number	PHS-CDC-99-74-20

Behavioral and Neurological Effects of Methyl Chloride.

Behavioral and Neurological Effects of Methyl Chloride.
PB274770

Publication Date	1976
Personal Author	Repko, J. D.; Jones, P. D.; Garcia, L. S.; Schneider, E. J.; Roseman, E.
Page Count	220
Abstract	Behavioral and neurological effects on workers exposed to methyl chloride were evaluated in 122 workers occupationally exposed to methyl chloride at 6 manufacturing plants using the solvent in fabricating processes. The duration of exposure correlated with airborne methyl chloride, with methyl chloride on the breath, and with blood hematocrit. Methyl chloride in the breath also related to airborne methyl chloride levels, while airborne methyl chloride and urine acidity correlated with hematocrit. Methyl chloride levels in ambient air and urine acidity were the two best indicators of workers' performance on behavioral tasks. No significant differences in the presence of abnormal neurological symptoms were noted between experimental and control groups. No significant differences were noted between exposed and non-exposed groups with respect to the presence of dysrhythmia. Methyl chloride adversely affected performance on cognitive time-sharing tasks and increased finger tremor. No relation was noted between exposure and psychological or personality tests.
Keywords	Organic solvents Chloromethanes Industrial medicine Toxicology Neurology Industrial atmospheres Air pollution Exposure Diagnosis Nervous system disorders Behavior disorders Performance(Human) Toxicity Hematology Blood chemical analysis Electroencephalography Behavioral toxicology Occupational safety and health Toxic substances Urinalysis
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57Y - Toxicology 57U - Public Health & Industrial Medicine 92B - Psychology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	Louisville Univ., KY. Performance Research Lab.; National Inst. for Occupational Safety and Health, Cincinnati, Ohio. Div.
Document Type	Technical Report
Title Note	Technical information rept.
NTIS Issue Number	197805
Contract Number	PHS-CDC-99-74-20