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Behavioral and Neurological Effects of Methyl Chloride.


PB274770

Publication Date 1976
Personal Author Repko, J. D.; Jones, P. D.; Garcia, L. S.; Schneider, E. J.; Roseman, E.
Page Count 220
Abstract Behavioral and neurological effects on workers exposed to methyl chloride were evaluated in 122 workers occupationally exposed to methyl chloride at 6 manufacturing plants using the solvent in fabricating processes. The duration of exposure correlated with airborne methyl chloride, with methyl chloride on the breath, and with blood hematocrit. Methyl chloride in the breath also related to airborne methyl chloride levels, while airborne methyl chloride and urine acidity correlated with hematocrit. Methyl chloride levels in ambient air and urine acidity were the two best indicators of workers' performance on behavioral tasks. No significant differences in the presence of abnormal neurological symptoms were noted between experimental and control groups. No significant differences were noted between exposed and non-exposed groups with respect to the presence of dysrhythmia. Methyl chloride adversely affected performance on cognitive time-sharing tasks and increased finger tremor. No relation was noted between exposure and psychological or personality tests.
Keywords
  • Organic solvents
  • Chloromethanes
  • Industrial medicine
  • Toxicology
  • Neurology
  • Industrial atmospheres
  • Air pollution
  • Exposure
  • Diagnosis
  • Nervous system disorders
  • Behavior disorders
  • Performance(Human)
  • Toxicity
  • Hematology
  • Blood chemical analysis
  • Electroencephalography
  • Behavioral toxicology
  • Occupational safety and health
  • Toxic substances
  • Urinalysis
Source Agency
  • National Institute for Occupational Safety and Health
NTIS Subject Category
  • 57Y - Toxicology
  • 57U - Public Health & Industrial Medicine
  • 92B - Psychology
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
Corporate Authors Louisville Univ., KY. Performance Research Lab.; National Inst. for Occupational Safety and Health, Cincinnati, Ohio. Div.
Document Type Technical Report
Title Note Technical information rept.
NTIS Issue Number 197805
Contract Number
  • PHS-CDC-99-74-20
Behavioral and Neurological Effects of Methyl Chloride.
Behavioral and Neurological Effects of Methyl Chloride.
PB274770

  • Organic solvents
  • Chloromethanes
  • Industrial medicine
  • Toxicology
  • Neurology
  • Industrial atmospheres
  • Air pollution
  • Exposure
  • Diagnosis
  • Nervous system disorders
  • Behavior disorders
  • Performance(Human)
  • Toxicity
  • Hematology
  • Blood chemical analysis
  • Electroencephalography
  • Behavioral toxicology
  • Occupational safety and health
  • Toxic substances
  • Urinalysis
  • National Institute for Occupational Safety and Health
  • 57Y - Toxicology
  • 57U - Public Health & Industrial Medicine
  • 92B - Psychology
  • 94D - Job Environment
  • 68G - Environmental Health & Safety
  • PHS-CDC-99-74-20
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