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Behavioral and Neurological Evaluation of Workers Exposed to Carbon Disulfide (CS2).

PB274764

Publication Date	1976
Personal Author	Tuttle, T. C.; Wood, G. D.; Grether, C. B.
Page Count	169
Abstract	A behavioral/neurological battery of tests was applied to a sample of workers occupationally exposed to carbon disulfide, together with neurological examination, and medical evaluation. Workers were also given psychometric tests of reaction time, coordination, visual search, short-term memory, and visual acuity. One hundred workers engaged in the manufacture of viscose rayon constituted the carbon disulfide-exposed group. Since ambient air levels of carbon disulfide could not be obtained within the viscose rayon plant, estimates of workers' exposure to carbon disulfide were based on detailed work history interviews with participants and results from an iodine azide test for urine metabolites of carbon disulfide. According to the total neurologic score for assessment of peripheral neuropathy, 13% of the carbon disulfide-exposed workers showed a probable or definite polyneuropathy. After correcting for age effects, neurologic indicators or ulnar nerve damage correlated significantly with indices of carbon disulfide-exposure, as did behavioral tests of reaction time, dexterity, rate of visual search, and perceptual organization.
Keywords	Organic solvents Carbon disulfide Toxicology Industrial medicine Neurology Organic sulfides Medical examination Nervous system disorders Behavior disorders Exposure Concentration(Composition) Standards Industrial atmospheres Air pollution Psychomotor tests Psychological tests Personnel Behavioral toxicology Occupational safety and health Toxic substances Air pollution effects(Humans) Threshold limit values
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57Y - Toxicology 57U - Public Health & Industrial Medicine 92B - Psychology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	Westinghouse Behavioral Services Center, Columbia, MD.; National Inst. for Occupational Safety and Health, Cincinnati, Ohio. Div.
Document Type	Technical Report
Title Note	Technical information rept.
NTIS Issue Number	197805
Contract Number	PHS-HSM-99-73-35

Behavioral and Neurological Evaluation of Workers Exposed to Carbon Disulfide (CS2).

Behavioral and Neurological Evaluation of Workers Exposed to Carbon Disulfide (CS2).
PB274764

Publication Date	1976
Personal Author	Tuttle, T. C.; Wood, G. D.; Grether, C. B.
Page Count	169
Abstract	A behavioral/neurological battery of tests was applied to a sample of workers occupationally exposed to carbon disulfide, together with neurological examination, and medical evaluation. Workers were also given psychometric tests of reaction time, coordination, visual search, short-term memory, and visual acuity. One hundred workers engaged in the manufacture of viscose rayon constituted the carbon disulfide-exposed group. Since ambient air levels of carbon disulfide could not be obtained within the viscose rayon plant, estimates of workers' exposure to carbon disulfide were based on detailed work history interviews with participants and results from an iodine azide test for urine metabolites of carbon disulfide. According to the total neurologic score for assessment of peripheral neuropathy, 13% of the carbon disulfide-exposed workers showed a probable or definite polyneuropathy. After correcting for age effects, neurologic indicators or ulnar nerve damage correlated significantly with indices of carbon disulfide-exposure, as did behavioral tests of reaction time, dexterity, rate of visual search, and perceptual organization.
Keywords	Organic solvents Carbon disulfide Toxicology Industrial medicine Neurology Organic sulfides Medical examination Nervous system disorders Behavior disorders Exposure Concentration(Composition) Standards Industrial atmospheres Air pollution Psychomotor tests Psychological tests Personnel Behavioral toxicology Occupational safety and health Toxic substances Air pollution effects(Humans) Threshold limit values
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57Y - Toxicology 57U - Public Health & Industrial Medicine 92B - Psychology 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	Westinghouse Behavioral Services Center, Columbia, MD.; National Inst. for Occupational Safety and Health, Cincinnati, Ohio. Div.
Document Type	Technical Report
Title Note	Technical information rept.
NTIS Issue Number	197805
Contract Number	PHS-HSM-99-73-35