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A Cross-Sectional Epidemiologic Survey of Vinyl Chloride Workers.

PB274193

Publication Date	1977
Personal Author	Waxweiler, R. J.; Falk, H.; McMichael, A.; Mallov, J. S.; Grivas, A. S.
Page Count	56
Abstract	The extent to which vinyl chloride monomer induces clinical detectable abnormalities among workers occupationally exposed was investigated during a cross-sectional medical survey at a chemical plant which had a polyvinyl chloride polymerization operation, a polyvinyl chloride fabrication operation, and a rubber tire production operation. The survey of 433 predominantly white male employees, divided into four vinyl chloride exposure groups (never, light, heavy, former), determined the prevalence of illnesses and abnormalities based on data gathered by interview, medical examination, blood and pulmonary function tests, liver scans, and hand and chest x-rays. Age-adjusted analyses indicated that hepatomegaly, central nervous system symptoms, diastolic hypertension and spouses' fetal wastage (the latter two statistically significant) were more prevalent among past or present vinyl chloride exposed workers than among controls. There was no excess of respiratory system problems, acroosteolysis, Raynaud's phenomenon, and chromosome aberrations as compared with industrial worker controls.
Keywords	Occupational diseases Industrial medicine Vinyl chloride Chemical industry Rubber industry Polyvinyl chloride Epidemiology Liver diseases Nervous system disorders Hypertension Pregnancy complications Abortion Toxicity Chlorohydrocarbons Health surveys Occupational safety and health Environmental health
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	National Inst. for Occupational Safety and Health, Cincinnati, Ohio. Div. of Surveillance, Hazard Evaluation and Field Studies.; Bureau of Epidemiology, Atlanta, Ga. Cancer and Birth Defects Div. North; Montefiore Hospital, Pittsburgh, Pa. Dept. of Medicine.
Supplemental Notes	Prepared in cooperation with Bureau of Epidemiology, Atlanta, Ga. Cancer and Birth Defects Div., North Carolina Univ. at Chapel Hill, N.C. Occupational Health Studies Group, and Montefiore Hospital, Pittsburgh, Pa. Dept. of Medicine.
Document Type	Technical Report
NTIS Issue Number	197804

A Cross-Sectional Epidemiologic Survey of Vinyl Chloride Workers.

A Cross-Sectional Epidemiologic Survey of Vinyl Chloride Workers.
PB274193

Publication Date	1977
Personal Author	Waxweiler, R. J.; Falk, H.; McMichael, A.; Mallov, J. S.; Grivas, A. S.
Page Count	56
Abstract	The extent to which vinyl chloride monomer induces clinical detectable abnormalities among workers occupationally exposed was investigated during a cross-sectional medical survey at a chemical plant which had a polyvinyl chloride polymerization operation, a polyvinyl chloride fabrication operation, and a rubber tire production operation. The survey of 433 predominantly white male employees, divided into four vinyl chloride exposure groups (never, light, heavy, former), determined the prevalence of illnesses and abnormalities based on data gathered by interview, medical examination, blood and pulmonary function tests, liver scans, and hand and chest x-rays. Age-adjusted analyses indicated that hepatomegaly, central nervous system symptoms, diastolic hypertension and spouses' fetal wastage (the latter two statistically significant) were more prevalent among past or present vinyl chloride exposed workers than among controls. There was no excess of respiratory system problems, acroosteolysis, Raynaud's phenomenon, and chromosome aberrations as compared with industrial worker controls.
Keywords	Occupational diseases Industrial medicine Vinyl chloride Chemical industry Rubber industry Polyvinyl chloride Epidemiology Liver diseases Nervous system disorders Hypertension Pregnancy complications Abortion Toxicity Chlorohydrocarbons Health surveys Occupational safety and health Environmental health
Source Agency	National Institute for Occupational Safety and Health
NTIS Subject Category	57U - Public Health & Industrial Medicine 94D - Job Environment 68G - Environmental Health & Safety
Corporate Authors	National Inst. for Occupational Safety and Health, Cincinnati, Ohio. Div. of Surveillance, Hazard Evaluation and Field Studies.; Bureau of Epidemiology, Atlanta, Ga. Cancer and Birth Defects Div. North; Montefiore Hospital, Pittsburgh, Pa. Dept. of Medicine.
Supplemental Notes	Prepared in cooperation with Bureau of Epidemiology, Atlanta, Ga. Cancer and Birth Defects Div., North Carolina Univ. at Chapel Hill, N.C. Occupational Health Studies Group, and Montefiore Hospital, Pittsburgh, Pa. Dept. of Medicine.
Document Type	Technical Report
NTIS Issue Number	197804