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Evaluation of the Validity of Cholesterol as a Biomarker for Suicide in Veterans.


PB2017102803

Publication Date 2017
Page Count 22
Abstract The purpose of this report was to investigate the use of total cholesterol as a biological marker for suicidality in a veteran sample. Previous research suggests low total cholesterol may increase the risk of suicidality in susceptible individuals by altering properties of the membranes in the brain. The low cholesterol levels appear to affect serotonin receptor exposure and cause a reduction of serotonin in the brain cells. This alters the reciprocal relationship between the serotonergic and dopaminergic systems and leads to an increase of impulsive, aggressive, self-directed aggressive behaviors, and suicidality in susceptible individuals.
Keywords
  • Cholesterol
  • Biomarker evaluation
  • Veteran
  • Serotonergic drugs
  • Evaluation
  • Suicide attempt
  • Biological markers
Source Agency
  • TriService Nursing Research Program/Uniform Services Univ. of the Health Sciences
NTIS Subject Category
  • 57A - Anatomy
  • 57E - Clinical Medicine
  • 57T - Psychiatry
  • 74 - Military Sciences
  • 92B - Psychology
Corporate Authors Rutgers - The State Univ., Newark, NJ.; TriService Nursing Research Program, Bethesda, MD.
Document Type Technical Report
Title Note Final rept., 15 Aug. 2015 - 14 Aug. 2016.
NTIS Issue Number 201726
Evaluation of the Validity of Cholesterol as a Biomarker for Suicide in Veterans.
Evaluation of the Validity of Cholesterol as a Biomarker for Suicide in Veterans.
PB2017102803

  • Cholesterol
  • Biomarker evaluation
  • Veteran
  • Serotonergic drugs
  • Evaluation
  • Suicide attempt
  • Biological markers
  • TriService Nursing Research Program/Uniform Services Univ. of the Health Sciences
  • 57A - Anatomy
  • 57E - Clinical Medicine
  • 57T - Psychiatry
  • 74 - Military Sciences
  • 92B - Psychology
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