National Technical Reports Library

The National Technical Information Service acquires, indexes, abstracts, and archives the largest collection of U.S. government-sponsored technical reports in existence. The NTRL offers online, free and open access to these authenticated government technical reports. Technical reports and documents in its repository may be available online for free either from the issuing federal agency, the U.S. Government Publishing Office’s Federal Digital System website, or through search engines.

Details

Lung Disease in Chinese Textile Workers, April 2010.

PB2013104695

Publication Date	2010
Page Count	8
Abstract	The proposed study is a competing continuation of R01 OH 02421. This proposal is designed to address unanswered questions regarding the respiratory health of workers chronically exposed to organic dust (specifically cotton dust) and endotoxin. Exposure to gram-negative bacterial endotoxin has been described in laboratory studies as producing acute respiratory symptoms and lung function change. Similar observations have not been reproduced in actual mill settings. To date, no other prospective epidemiologic study has addressed the relative contributions of cotton dust and endotoxin in producing both acute and chronic respiratory effects. In addition, we will examine the long-term effects of removal by retirement from exposure on respiratory health status. This is possible because of documented accessibility to workers who have left the workforce. The importance of endotoxin in causing pulmonary effects is important not only in the cotton textile industry, but also in a number multitude of other environments where significant levels of airborne endotoxin are encountered. The study population (closed cohort) that has been followed since 1981 and is unusually well-suited for epidemiologic study due to: low turnover, very low smoking prevalence among women workers, reliable baseline data, a suitable comparison group studied in identical fashion, excellent cooperation among industry officials, union and the collaborative research team, access to subjects who have retired or left the industry in disability, and cost-efficiency. The population included 447 cotton textile and 465 silk textile workers first surveyed in 1981. Follow-up surveys were conducted in 1986, 1992, and 1996, 2001 and 2006 with excellent follow-up.
Keywords	Respiratory system disorders Textiles industry Cotton dust Airborne dusts Bacteria Dust exposure Endotoxins Epidemiology Lung diseases Mill workers Occupational exposure Organic compounds Pulmonary system disorders Surveys
Source Agency	National Institute for Occupational Safety and Health
Corporate Authors	Harvard School of Public Health, Boston, MA.; National Inst. for Occupational Safety and Health, Washington, DC.
Supplemental Notes	See also PB91-184481 and PB97-151773. Sponsored by National Inst. for Occupational Safety and Health, Washington, DC.
Document Type	Technical Report
NTIS Issue Number	201311
Contract Number	R01-OH02421-13

Lung Disease in Chinese Textile Workers, April 2010.

Lung Disease in Chinese Textile Workers, April 2010.
PB2013104695

Publication Date	2010
Page Count	8
Abstract	The proposed study is a competing continuation of R01 OH 02421. This proposal is designed to address unanswered questions regarding the respiratory health of workers chronically exposed to organic dust (specifically cotton dust) and endotoxin. Exposure to gram-negative bacterial endotoxin has been described in laboratory studies as producing acute respiratory symptoms and lung function change. Similar observations have not been reproduced in actual mill settings. To date, no other prospective epidemiologic study has addressed the relative contributions of cotton dust and endotoxin in producing both acute and chronic respiratory effects. In addition, we will examine the long-term effects of removal by retirement from exposure on respiratory health status. This is possible because of documented accessibility to workers who have left the workforce. The importance of endotoxin in causing pulmonary effects is important not only in the cotton textile industry, but also in a number multitude of other environments where significant levels of airborne endotoxin are encountered. The study population (closed cohort) that has been followed since 1981 and is unusually well-suited for epidemiologic study due to: low turnover, very low smoking prevalence among women workers, reliable baseline data, a suitable comparison group studied in identical fashion, excellent cooperation among industry officials, union and the collaborative research team, access to subjects who have retired or left the industry in disability, and cost-efficiency. The population included 447 cotton textile and 465 silk textile workers first surveyed in 1981. Follow-up surveys were conducted in 1986, 1992, and 1996, 2001 and 2006 with excellent follow-up.
Keywords	Respiratory system disorders Textiles industry Cotton dust Airborne dusts Bacteria Dust exposure Endotoxins Epidemiology Lung diseases Mill workers Occupational exposure Organic compounds Pulmonary system disorders Surveys
Source Agency	National Institute for Occupational Safety and Health
Corporate Authors	Harvard School of Public Health, Boston, MA.; National Inst. for Occupational Safety and Health, Washington, DC.
Supplemental Notes	See also PB91-184481 and PB97-151773. Sponsored by National Inst. for Occupational Safety and Health, Washington, DC.
Document Type	Technical Report
NTIS Issue Number	201311
Contract Number	R01-OH02421-13