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In Vivo Rabbit Model of Finger Musculoskeletal Disorders.


PB2011109679

Publication Date 2008
Personal Author King, K. B.; Rempel, D.
Page Count 17
Abstract The goal of this project was to develop and validate a method for testing the biomechanical risk factors for occupational hand injury due to overuse. This project focused on the risk factors of force and frequency in order to determine how hard and fast a worker can perform a repeating hand task without injury. This is an important problem for the United States workforce because manual handling and similar tasks are on the rise along with upper musculoskeletal disorders. Even some jobs considered white collar such as dental hygiene are seeing increasing hand injuries which may be due to forceful and repetitive hand tasks like periodontal scaling. The design approach of this project was to measure the biological changes in finger joint tissues following repeated grip-like motions with groups of experiments testing different force levels and different frequency levels. Because measuring biological effects of joint tissues requires destructive methods (biochemistry, histology, etc.), it was necessary to first create an animal model for cyclical finger joint loading. Thus, the first aim of the project was to create an in vivo model that would simulate hand tasks using occupationally relevant loads and speeds. The second and third aims of the project were to measure the structural and biochemical changes resulting from the loading and to determine if these changes are co-localized. The fourth aim of the project was to test different force levels and different frequency levels to determine if thresholds of loading exist.
Keywords
  • Laboratory animals
  • Musculoskeletal system disorders
  • Animal studies
  • Muscles
  • Repetitive work
  • Trauma disorders
  • Finger(Anatomy)
  • Biomechanics
  • Hand injures
  • In vivo studies
  • Risk analysis
  • Injury prevention
  • Exposure levels
Source Agency
  • National Institute for Occupational Safety and Health
Corporate Authors Colorado Univ. at Denver.; National Inst. for Occupational Safety and Health, Washington, DC.
Supplemental Notes Sponsored by National Inst. for Occupational Safety and Health, Washington, DC.
Document Type Technical Report
NTIS Issue Number 201117
In Vivo Rabbit Model of Finger Musculoskeletal Disorders.
In Vivo Rabbit Model of Finger Musculoskeletal Disorders.
PB2011109679

  • Laboratory animals
  • Musculoskeletal system disorders
  • Animal studies
  • Muscles
  • Repetitive work
  • Trauma disorders
  • Finger(Anatomy)
  • Biomechanics
  • Hand injures
  • In vivo studies
  • Risk analysis
  • Injury prevention
  • Exposure levels
  • National Institute for Occupational Safety and Health
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