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Details

Acetaminophen Use for Preemptive Analgesia.

PB2009114652

Publication Date	2001
Personal Author	Walizer, E. M.
Page Count	48
Abstract	A randomized, double-blind, placebo-controlled clinical trial was used to determine if preemptive acetaminophen can (1) significantly diminish the postoperative perception of pain in patients having reduction mammoplasty, (2) significantly reduce postoperative need for narcotic analgesia in these patients, and (3) identify correlations between previous pain experiences and self-reported postoperative pain. A convenience sample of 119 women attending the plastic surgery clinic at Walter Reed Army Medical Center was used. Women receiving acetaminophen had significantly less pain and required significantly less narcotic in the first 4 postoperative hours. No differences were found for opioid side effects, ability to perform daily activities, overall satisfaction with pain management, or length of stay. Numerous moderate associations were identified between history of painful episodes and self-perceived pain. Using acetaminophen for preemptive analgesia has important implications for clinical practice as well as military health care. Improvements in patient care would be dramatic.
Keywords	Acetaminophen Analgesia Clinical trials Pain management Females Plastic surgery Mamoplasty Narcotics
Source Agency	TriService Nursing Research Program/Uniform Services Univ. of the Health Sciences
Corporate Authors	Walter Reed Army Medical Center, Washington, DC.; TriService Nursing Research Program, Bethesda, MD.
Supplemental Notes	Sponsored by TriService Nursing Research Program, Bethesda, MD.
Document Type	Technical Report
Title Note	Final rept., Sep 96-Jun 01.
NTIS Issue Number	200926
Contract Number	N96-026

Acetaminophen Use for Preemptive Analgesia.

Acetaminophen Use for Preemptive Analgesia.
PB2009114652

Publication Date	2001
Personal Author	Walizer, E. M.
Page Count	48
Abstract	A randomized, double-blind, placebo-controlled clinical trial was used to determine if preemptive acetaminophen can (1) significantly diminish the postoperative perception of pain in patients having reduction mammoplasty, (2) significantly reduce postoperative need for narcotic analgesia in these patients, and (3) identify correlations between previous pain experiences and self-reported postoperative pain. A convenience sample of 119 women attending the plastic surgery clinic at Walter Reed Army Medical Center was used. Women receiving acetaminophen had significantly less pain and required significantly less narcotic in the first 4 postoperative hours. No differences were found for opioid side effects, ability to perform daily activities, overall satisfaction with pain management, or length of stay. Numerous moderate associations were identified between history of painful episodes and self-perceived pain. Using acetaminophen for preemptive analgesia has important implications for clinical practice as well as military health care. Improvements in patient care would be dramatic.
Keywords	Acetaminophen Analgesia Clinical trials Pain management Females Plastic surgery Mamoplasty Narcotics
Source Agency	TriService Nursing Research Program/Uniform Services Univ. of the Health Sciences
Corporate Authors	Walter Reed Army Medical Center, Washington, DC.; TriService Nursing Research Program, Bethesda, MD.
Supplemental Notes	Sponsored by TriService Nursing Research Program, Bethesda, MD.
Document Type	Technical Report
Title Note	Final rept., Sep 96-Jun 01.
NTIS Issue Number	200926
Contract Number	N96-026