National Technical Reports Library

The National Technical Information Service acquires, indexes, abstracts, and archives the largest collection of U.S. government-sponsored technical reports in existence. The NTRL offers online, free and open access to these authenticated government technical reports. Technical reports and documents in its repository may be available online for free either from the issuing federal agency, the U.S. Government Publishing Office’s Federal Digital System website, or through search engines.

Details

Effects of Three Modes of Mechanical Ventilation.

PB2009107904

Publication Date	1997
Personal Author	Pierce, J.
Page Count	30
Abstract	Mechanical ventilation has been used in critically ill patients for years to improve their ventilation and oxygenation. A new mode of mechanical ventilation called pressure regulated volume control (PRVC) has been developed which differs from the traditional modes of volume control (VC) and pressure control (PC) ventilation. The aim of this study was to investigate the differences in diaphragm shortening during PRVC versus VC and PC. Sprague Dawley rats were used and sequentially ventilated with PRVC, VC or PC. Within each mode, the tidal volume was increased from 3 ml to 12 ml in increments of 3 ml. Measurements of blood pressure, central venous pressure, diaphragm shortening, intrathoracic pressure, end-tidal CO2 and peak inspiratory pressure were taken throughout the experiment. There were no differences observed in the peak inspiratory pressure among the modes at all tidal volumes which suggests that compliances and airway resistances were the same for the three modes. In the PRVC mode, diaphragm shortening was significantly less than in the VC or PC mode. The difference in diaphragm shortening is believed to be associated to the changes in the resting length of the diaphragm. Consequently, PRVC affected the expansion of the chest differently than VC or PC. Further study of the movement of the diaphragm over long periods of ventilation is needed to understand the effect of this muscle when begin weaning from mechanical ventilation.
Keywords	Ventilation Patients Oxygenation Rats Medical equipment Laboratory animals Critical illness Military Mechanical ventilation Diaphragm shortening Pressure regulated volume control(PRVC)
Source Agency	TriService Nursing Research Program/Uniform Services Univ. of the Health Sciences
Corporate Authors	Kansas Univ., Kansas City. School of Nursing.; TriService Nursing Research Program, Bethesda, MD.
Supplemental Notes	Supersedes PB2003-105479. Sponsored by TriService Nursing Research Program, Bethesda, MD.
Document Type	Technical Report
Title Note	Final rept., 22 Aug 95-28 Feb 97.
NTIS Issue Number	200915
Contract Number	905-95-Z-0042

Effects of Three Modes of Mechanical Ventilation.

Effects of Three Modes of Mechanical Ventilation.
PB2009107904

Publication Date	1997
Personal Author	Pierce, J.
Page Count	30
Abstract	Mechanical ventilation has been used in critically ill patients for years to improve their ventilation and oxygenation. A new mode of mechanical ventilation called pressure regulated volume control (PRVC) has been developed which differs from the traditional modes of volume control (VC) and pressure control (PC) ventilation. The aim of this study was to investigate the differences in diaphragm shortening during PRVC versus VC and PC. Sprague Dawley rats were used and sequentially ventilated with PRVC, VC or PC. Within each mode, the tidal volume was increased from 3 ml to 12 ml in increments of 3 ml. Measurements of blood pressure, central venous pressure, diaphragm shortening, intrathoracic pressure, end-tidal CO2 and peak inspiratory pressure were taken throughout the experiment. There were no differences observed in the peak inspiratory pressure among the modes at all tidal volumes which suggests that compliances and airway resistances were the same for the three modes. In the PRVC mode, diaphragm shortening was significantly less than in the VC or PC mode. The difference in diaphragm shortening is believed to be associated to the changes in the resting length of the diaphragm. Consequently, PRVC affected the expansion of the chest differently than VC or PC. Further study of the movement of the diaphragm over long periods of ventilation is needed to understand the effect of this muscle when begin weaning from mechanical ventilation.
Keywords	Ventilation Patients Oxygenation Rats Medical equipment Laboratory animals Critical illness Military Mechanical ventilation Diaphragm shortening Pressure regulated volume control(PRVC)
Source Agency	TriService Nursing Research Program/Uniform Services Univ. of the Health Sciences
Corporate Authors	Kansas Univ., Kansas City. School of Nursing.; TriService Nursing Research Program, Bethesda, MD.
Supplemental Notes	Supersedes PB2003-105479. Sponsored by TriService Nursing Research Program, Bethesda, MD.
Document Type	Technical Report
Title Note	Final rept., 22 Aug 95-28 Feb 97.
NTIS Issue Number	200915
Contract Number	905-95-Z-0042