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The National Technical Information Service acquires, indexes, abstracts, and archives the largest collection of U.S. government-sponsored technical reports in existence. The NTRL offers online, free and open access to these authenticated government technical reports. Technical reports and documents in its repository may be available online for free either from the issuing federal agency, the U.S. Government Publishing Office’s Federal Digital System website, or through search engines.

Details

Biosensors and Methods for Their Use.

PB2007100778

Publication Date	2001
Personal Author	Ho, C. M.; Wang, T. H.
Page Count	29
Abstract	The invention disclosed herein provides biosensors and methods which increase the sensitivity of assays of optically labelled molecules fluoresently tagged polypeptides and polynucleotides while decreasing the sample volume required for detection. By integrating reflective sidewalls into the receptacles used in such assays, the signal-to-noise ratio of the optical signal is increased significantly. Typically the receptacles are microchannels.
Keywords	Detectors Assaying Molecules Polypeptides Polynucleotides Detection Optical properties Patent applications Biosensors
Source Agency	Government Patent Navy
Corporate Authors	Gates and Cooper, Los Angeles, CA.; Department of the Navy, Washington, DC.
Supplemental Notes	Sponsored by Department of Energy, Washington, DC.
Document Type	Patent Application
NTIS Issue Number	200704
Contract Number	DON-N66001-96-C83632

Biosensors and Methods for Their Use.

Biosensors and Methods for Their Use.
PB2007100778

Publication Date	2001
Personal Author	Ho, C. M.; Wang, T. H.
Page Count	29
Abstract	The invention disclosed herein provides biosensors and methods which increase the sensitivity of assays of optically labelled molecules fluoresently tagged polypeptides and polynucleotides while decreasing the sample volume required for detection. By integrating reflective sidewalls into the receptacles used in such assays, the signal-to-noise ratio of the optical signal is increased significantly. Typically the receptacles are microchannels.
Keywords	Detectors Assaying Molecules Polypeptides Polynucleotides Detection Optical properties Patent applications Biosensors
Source Agency	Government Patent Navy
Corporate Authors	Gates and Cooper, Los Angeles, CA.; Department of the Navy, Washington, DC.
Supplemental Notes	Sponsored by Department of Energy, Washington, DC.
Document Type	Patent Application
NTIS Issue Number	200704
Contract Number	DON-N66001-96-C83632