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Mutagenicity Evaluation of 1,3-dioxolane with Cover Letter dated 013183.


OTS0510987

Publication Date 1983
Page Count 12
Abstract The mutagenicity of 1,3-dioxolane was evaluated in Salmonella tester strains TA98, TA100, TA1535, TA1537 and TA1538 (Ames Test), both in the presence and absence of added metabolic activation by Aroclor-induced rat liver S9 fraction. Based on preliminary toxicity determinations, 1,3-dioxolane, diluted in DMSO, was tested at concentrations up to 1000ug/plate using the plate incorporation technique. 1,3-Dioxolane did not produce a reproducible positive response in any tester strain with or without metabolic activation.
Keywords
  • Toxicology
  • Health effects
  • Goodyear tire & rubber co
  • Toxic substances
  • 1,3-dioxolane
  • Laboratory animals
  • Genotoxicity
  • Gene mutations
  • Bacteria
  • In vitro
  • CAS No. 646-06-0
Source Agency
  • VAS TECH OTS SCANNING PROJECT
NTIS Subject Category
  • 57Y - Toxicology
  • 57U - Public Health & Industrial Medicine
  • 68G - Environmental Health & Safety
  • 99 - Chemistry
  • 44G - Environmental & Occupational Factors
Corporate Authors Environmental Protection Agency, Washington, DC. Office of Toxic
Document Type Technical Report
NTIS Issue Number 200820
Mutagenicity Evaluation of 1,3-dioxolane with Cover Letter dated 013183.
Mutagenicity Evaluation of 1,3-dioxolane with Cover Letter dated 013183.
OTS0510987

  • Toxicology
  • Health effects
  • Goodyear tire & rubber co
  • Toxic substances
  • 1,3-dioxolane
  • Laboratory animals
  • Genotoxicity
  • Gene mutations
  • Bacteria
  • In vitro
  • CAS No. 646-06-0
  • VAS TECH OTS SCANNING PROJECT
  • 57Y - Toxicology
  • 57U - Public Health & Industrial Medicine
  • 68G - Environmental Health & Safety
  • 99 - Chemistry
  • 44G - Environmental & Occupational Factors
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