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Toxicity and Health Hazard Summary with Cover Letters. Alkyl Phthalates and Dicyclohexyl Phthalate.

OTS0206525

Publication Date	1984
Page Count	32
Abstract	This compound is at most only slightly toxic in rats having a LD50 both orally and intraperitoneally of >3200 mg/kg. In mice the oral LD50 is >3200 while the intraperitoneal LD50 is1600 mg/kg, When held in content with depilated skin of guinea pigs, it proved to be a slight skin irritant, and there was no definite evidence of toxic effects caused by skin application. Several crystals dropped into the conjunctival sac of a rabbit's eye caused only slight irritation and no corneal damage. The material is not a sensitizer in guinea pigs.
Keywords	Toxicity Eye irritation Lethal doses Rats Laboratory animals Toxic substances Hazardous materials Mice Skin irritation Guinea pigs Alkyl phthalates Dicyclohexyl phthalate CAS No. 84-61-7
Source Agency	Office of Toxic Substances
Corporate Authors	Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic
Supplemental Notes	The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC.
Document Type	Technical Report
NTIS Issue Number	200814

Toxicity and Health Hazard Summary with Cover Letters. Alkyl Phthalates and Dicyclohexyl Phthalate.

Toxicity and Health Hazard Summary with Cover Letters. Alkyl Phthalates and Dicyclohexyl Phthalate.
OTS0206525

Publication Date	1984
Page Count	32
Abstract	This compound is at most only slightly toxic in rats having a LD50 both orally and intraperitoneally of >3200 mg/kg. In mice the oral LD50 is >3200 while the intraperitoneal LD50 is1600 mg/kg, When held in content with depilated skin of guinea pigs, it proved to be a slight skin irritant, and there was no definite evidence of toxic effects caused by skin application. Several crystals dropped into the conjunctival sac of a rabbit's eye caused only slight irritation and no corneal damage. The material is not a sensitizer in guinea pigs.
Keywords	Toxicity Eye irritation Lethal doses Rats Laboratory animals Toxic substances Hazardous materials Mice Skin irritation Guinea pigs Alkyl phthalates Dicyclohexyl phthalate CAS No. 84-61-7
Source Agency	Office of Toxic Substances
Corporate Authors	Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic
Supplemental Notes	The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC.
Document Type	Technical Report
NTIS Issue Number	200814