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Report on Oral LD50 in Rats.


OTS0206125

Publication Date 1978
Page Count 63
Abstract This report contains a summary of the data compiled during the evaluation of the test material. The report is organized to present the results in a concise and easily interpretable manner. The first part contains items I - IV and provides sponsor and compound identification information, type of assay and the protocol reference number. All protocol references indicate a standard procedure described in the Litton Bionetics, Inc., Screening Program for the Identification of Potential Mutagens and Carcinogens. Item V identifies the tables and/or figures containing the data used by the Study Director in interpreting the test results (item VI). The second part of the report, entitled PROTOCOL, describes, in detail, the materials and procedures employed in conducting the evaluation. This part of the report also contains evaluation criteria, standard operating procedures and any appendices. These are included to acquaint the sponsor with the methods used to develop and analyze the test results. All test and control results presented in this report are supported by fully documented raw data which are permanently maintained in the files of the Department of Genetics and Cell Biology. In terms of reportable substances our submission is organized and may be summarized as follows: Chlorinated Paraffin, Toluene, Epoxides, Phthalate Ester, Xylene, Methyl Ethyl Ketone, Methyl Isobutyl Ketone, Fropylene Oxide, Trieresyl Phosphate, and Trixylenyl Phosphate.
Keywords
  • Mutagenesis
  • Carcinogenesis
  • Carcinogens
  • Mutagens
  • Toxicity
  • Rats
  • Laboratory animals
  • Standard operating procedures
  • Evaluation criteria
  • Lethal doses
  • Screening
  • Ingestion
  • Necropsy
  • Protocols
  • Pharmacological effects
  • Aryl phosphates
  • Tricresyl phosphate
  • CAS No. 1330-78-5
Source Agency
  • Office of Toxic Substances
Corporate Authors Mobil Oil Corp., New York.; Environmental Protection Agency, Washington, DC. Office of Toxic
Supplemental Notes The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC.
Document Type Technical Report
NTIS Issue Number 200808
Report on Oral LD50 in Rats.
Report on Oral LD50 in Rats.
OTS0206125

  • Mutagenesis
  • Carcinogenesis
  • Carcinogens
  • Mutagens
  • Toxicity
  • Rats
  • Laboratory animals
  • Standard operating procedures
  • Evaluation criteria
  • Lethal doses
  • Screening
  • Ingestion
  • Necropsy
  • Protocols
  • Pharmacological effects
  • Aryl phosphates
  • Tricresyl phosphate
  • CAS No. 1330-78-5
  • Office of Toxic Substances
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