National Technical Reports Library

The National Technical Information Service acquires, indexes, abstracts, and archives the largest collection of U.S. government-sponsored technical reports in existence. The NTRL offers online, free and open access to these authenticated government technical reports. Technical reports and documents in its repository may be available online for free either from the issuing federal agency, the U.S. Government Publishing Office’s Federal Digital System website, or through search engines.

Details

Preliminary Toxicological Study of Irganox 1010.

LA8037MS

Publication Date	1979
Personal Author	Drake, G. A.; London, J. E.; Smith, D. M.; Thomas, R. G.
Page Count	10
Abstract	Acute oral LD/sub 50/30/ values for mice and rats receiving Irganox 1010 were found to be greater than 5 g/kg. According to classical guidelines, this material would be considered slightly toxic or practically nontoxic in both species. Skin applicaton studies in rabbits showed the material to be nonirritating. Eye irritation studies, also in the rabbit, showed that Irganox 1010 was a mild but transitory irritant. The sensitizaton study in guinea pigs did not show the material to be deleterious. (ERA citation 05:003659)
Keywords	Antioxidants Biological effects Experimental data Eyes Guinea pigs Immunity Isolated values Mice Oral administration Rabbits Rats Single intake Skin Toxicity Toxicology Toxic substances ERDA/560305
Source Agency	Technical Information Center Oak Ridge Tennessee
NTIS Subject Category	57Y - Toxicology 57O - Pathology
Corporate Authors	Los Alamos Scientific Lab., NM.; Department of Energy.
Document Type	Technical Report
NTIS Issue Number	198018
Contract Number	W-7405-ENG-36

Preliminary Toxicological Study of Irganox 1010.

Preliminary Toxicological Study of Irganox 1010.
LA8037MS

Publication Date	1979
Personal Author	Drake, G. A.; London, J. E.; Smith, D. M.; Thomas, R. G.
Page Count	10
Abstract	Acute oral LD/sub 50/30/ values for mice and rats receiving Irganox 1010 were found to be greater than 5 g/kg. According to classical guidelines, this material would be considered slightly toxic or practically nontoxic in both species. Skin applicaton studies in rabbits showed the material to be nonirritating. Eye irritation studies, also in the rabbit, showed that Irganox 1010 was a mild but transitory irritant. The sensitizaton study in guinea pigs did not show the material to be deleterious. (ERA citation 05:003659)
Keywords	Antioxidants Biological effects Experimental data Eyes Guinea pigs Immunity Isolated values Mice Oral administration Rabbits Rats Single intake Skin Toxicity Toxicology Toxic substances ERDA/560305
Source Agency	Technical Information Center Oak Ridge Tennessee
NTIS Subject Category	57Y - Toxicology 57O - Pathology
Corporate Authors	Los Alamos Scientific Lab., NM.; Department of Energy.
Document Type	Technical Report
NTIS Issue Number	198018
Contract Number	W-7405-ENG-36