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PointCloudExplore 2: Visual Exploration of 3D Gene Expression.


DE2008928314

Publication Date 2008
Personal Author Hagen, H.; Flowlkew, C. C.; Hamann, B.; Knowles, D. W.; Malik, J.
Page Count 14
Abstract To better understand how developmental regulatory networks are defined in the genome sequence, the Berkeley Drosophila Transcription Network Project (BDNTP) has developed a suite of methods to describe 3D gene expression data, i.e., the output of the network at cellular resolution for multiple time points. To allow researchers to explore these novel data sets we have developed PointCloudXplore (PCX). In PCX we have linked physical and information visualization views via the concept of brushing (cell selection). For each view dedicated operations for performing selection of cells are available. In PCX, all cell selections are stored in a central management system. Cells selected in one view can in this way be highlighted in any view allowing further cell subset properties to be determined. Complex cell queries can be defined by combining different cell selections using logical operations such as AND, OR, and NOT. Here we are going to provide an overview of PointCloudXplore 2 (PCX2), the latest publicly available version of PCX. PCX2 has shown to be an effective tool for visual exploration of 3D gene expression data.
Keywords
  • Genes
  • Visualization
  • Three dimensional image
  • Genome mutations
  • Cells(Biology)
  • Resolution
  • Data analysis
  • Gene expression
  • Cell selection
Source Agency
  • Technical Information Center Oak Ridge Tennessee
Corporate Authors Lawrence Berkeley National Lab., CA. Environmental Energy Technologies Div.; California Univ., Berkeley. Computer Science Div.; California Univ., Berkeley. Dept. of Molecular Biology.; Department of Energy, Washington, DC.
Supplemental Notes Prepared in cooperation with California Univ., Berkeley. Computer Science Div., California Univ., Berkeley. Computer Science Div. and California Univ., Berkeley. Dept. of Molecular Biology. Sponsored by Department of Energy, Washington, DC.
Document Type Technical Report
NTIS Issue Number 200824
Contract Number
  • DE-AC02-05CH11231
PointCloudExplore 2: Visual Exploration of 3D Gene Expression.
PointCloudExplore 2: Visual Exploration of 3D Gene Expression.
DE2008928314

  • Genes
  • Visualization
  • Three dimensional image
  • Genome mutations
  • Cells(Biology)
  • Resolution
  • Data analysis
  • Gene expression
  • Cell selection
  • Technical Information Center Oak Ridge Tennessee
  • DE-AC02-05CH11231
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