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Genomic and Genetic Approaches to Solvent Tolerance.


DE2005840821

Publication Date 2005
Page Count 14
Abstract The proposed research is to understand and exploit the molecular basis that determines tolerance of the industrially important anaerobic clostridia to solvents. Furthermore, we aim to develop general genomic and metabolic engineering strategies for understanding the molecular basis of tolerance to chemicals and for developing tolerant strains. Our hypothesis is that the molecular basis of what makes bacterial cells able to withstand high solvent concentrations can be used to metabolically engineer cells so that they can tolerate higher concentrations of solvents and related chemicals.
Keywords
  • Solvents
  • Tolerance
  • Genetics
  • Genomes
  • Strains
Source Agency
  • Technical Information Center Oak Ridge Tennessee
Corporate Authors Northwestern Univ., Chicago, IL.
Document Type Technical Report
Title Note Rept. for 1 Oct 03-31 Mar 04.
NTIS Issue Number 200605
Genomic and Genetic Approaches to Solvent Tolerance.
Genomic and Genetic Approaches to Solvent Tolerance.
DE2005840821

  • Solvents
  • Tolerance
  • Genetics
  • Genomes
  • Strains
  • Technical Information Center Oak Ridge Tennessee
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