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Effects of Scatter Modeling on Time-Activity Curves Estimated Directly from Dynamic SPECT Projections.

DE2004828133

Publication Date	2003
Personal Author	Reutter, B. W.; Gullberg, G. T.; Huesman, R. H.
Page Count	10
Abstract	Quantitative analysis of uptake and washout of cardiac single photon emission computed tomography (SPECT) radiopharmaceuticals has the potential to provide better contrast between healthy and diseased tissue, compared to conventional reconstruction of static images. Previously, we used B-splines to model time-activity curves (TACs) for segmented volumes of interest and developed fast least-squares algorithms to estimate spline TAC coefficients and their statistical uncertainties directly from dynamic SPECT projection data.
Keywords	Single photon emission computed tomography Image processing Blood Collimators Liver Myocardium Diagnostic uses Algorithms
Source Agency	Technical Information Center Oak Ridge Tennessee
Corporate Authors	Lawrence Berkeley National Lab., CA.; Department of Energy, Washington, DC.
Supplemental Notes	Sponsored by Department of Energy, Washington, DC.
Document Type	Technical Report
NTIS Issue Number	200512

Effects of Scatter Modeling on Time-Activity Curves Estimated Directly from Dynamic SPECT Projections.

Effects of Scatter Modeling on Time-Activity Curves Estimated Directly from Dynamic SPECT Projections.
DE2004828133

Publication Date	2003
Personal Author	Reutter, B. W.; Gullberg, G. T.; Huesman, R. H.
Page Count	10
Abstract	Quantitative analysis of uptake and washout of cardiac single photon emission computed tomography (SPECT) radiopharmaceuticals has the potential to provide better contrast between healthy and diseased tissue, compared to conventional reconstruction of static images. Previously, we used B-splines to model time-activity curves (TACs) for segmented volumes of interest and developed fast least-squares algorithms to estimate spline TAC coefficients and their statistical uncertainties directly from dynamic SPECT projection data.
Keywords	Single photon emission computed tomography Image processing Blood Collimators Liver Myocardium Diagnostic uses Algorithms
Source Agency	Technical Information Center Oak Ridge Tennessee
Corporate Authors	Lawrence Berkeley National Lab., CA.; Department of Energy, Washington, DC.
Supplemental Notes	Sponsored by Department of Energy, Washington, DC.
Document Type	Technical Report
NTIS Issue Number	200512