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Positron Emission Mammography with Multiple Angle Acquisition.

DE2003805771

Publication Date	2002
Page Count	10
Abstract	Positron emission mammography (PEM) of F-18 fluorodeoxyglucose (FbG) uptake in breast tumors with dedicated detectors typically has been accomplished with two planar detectors in a fixed position with the breast under compression. The potential use of PEM imaging at two detector positions to guide stereotactic breast biopsy has motivated us to use PEM coincidence data acquired at two or more detector positions together in a single image reconstruction. Multiple angle PEM acquisition and iterative image reconstruction were investigated using point source and compressed breast phantom acquisitions with 5, 9, 12 and 15 mm diameter spheres and a simulated tumor: background activity concentration ratio of 6:1. Additional study is needed to better understand the performance of limited angle tomography for PEM. PEM tomography experiments with complete angular sampling are planned.
Keywords	Mammary glands Tomography Neoplasms Algoriths Biopsy Compression Concentration ratio Fluorodeoxyglucose Metrics Phantoms Point sources Positrons Sampling Resolution
Source Agency	Technical Information Center Oak Ridge Tennessee
Corporate Authors	Department of Energy, Washington, DC.
Document Type	Technical Report
NTIS Issue Number	200321

Positron Emission Mammography with Multiple Angle Acquisition.

Positron Emission Mammography with Multiple Angle Acquisition.
DE2003805771

Publication Date	2002
Page Count	10
Abstract	Positron emission mammography (PEM) of F-18 fluorodeoxyglucose (FbG) uptake in breast tumors with dedicated detectors typically has been accomplished with two planar detectors in a fixed position with the breast under compression. The potential use of PEM imaging at two detector positions to guide stereotactic breast biopsy has motivated us to use PEM coincidence data acquired at two or more detector positions together in a single image reconstruction. Multiple angle PEM acquisition and iterative image reconstruction were investigated using point source and compressed breast phantom acquisitions with 5, 9, 12 and 15 mm diameter spheres and a simulated tumor: background activity concentration ratio of 6:1. Additional study is needed to better understand the performance of limited angle tomography for PEM. PEM tomography experiments with complete angular sampling are planned.
Keywords	Mammary glands Tomography Neoplasms Algoriths Biopsy Compression Concentration ratio Fluorodeoxyglucose Metrics Phantoms Point sources Positrons Sampling Resolution
Source Agency	Technical Information Center Oak Ridge Tennessee
Corporate Authors	Department of Energy, Washington, DC.
Document Type	Technical Report
NTIS Issue Number	200321