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2-Acetyl and 2-Propionylpyridine Thiosemicarbazones as Antimalarials.


ADD010374

Publication Date 1983
Personal Author Klayman, D. L.; Scovill, J. P.; Bartosevich, J. F.; Mason, C. J.; Griffin, T. S.
Page Count 8
Abstract This invention relates to various 2-acetyl- and 2-propionylpyridine thiosemicarbazones which are substituted on the 4-nitrogen atom. These compounds are useful in the treatment of gonorrhea and, in addition, many are useful either in the treatment of malaria or bacterial infection. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones.
Keywords
  • Patents
  • Antimalarials
  • Amines
  • Thiourea
  • Synthesis(Chemistry)
  • Methyl radicals
  • Ethyl radicals
  • Alkyl radicals
  • Heterocyclic compounds
  • Gonorrhea
  • Malaria
  • Infectious diseases
  • Thiosemicarbazones
  • Pyridine thiosemicarbazone/propionyl
  • Thiosemicarbazone/acetyl
Source Agency
  • Government Patents Army
NTIS Subject Category
  • 90B - Chemistry
  • 90D - Biology & Medicine
  • 99D - Basic & Synthetic Chemistry
  • 57Q - Pharmacology & Pharmacological Chemistry
Corporate Authors Department of the Army, Washington, DC.
Supplemental Notes Supersedes PAT-APPL-6-311 368.
Document Type Patent
Title Note Patent.
NTIS Issue Number 198323
2-Acetyl and 2-Propionylpyridine Thiosemicarbazones as Antimalarials.
2-Acetyl and 2-Propionylpyridine Thiosemicarbazones as Antimalarials.
ADD010374

  • Patents
  • Antimalarials
  • Amines
  • Thiourea
  • Synthesis(Chemistry)
  • Methyl radicals
  • Ethyl radicals
  • Alkyl radicals
  • Heterocyclic compounds
  • Gonorrhea
  • Malaria
  • Infectious diseases
  • Thiosemicarbazones
  • Pyridine thiosemicarbazone/propionyl
  • Thiosemicarbazone/acetyl
  • Government Patents Army
  • 90B - Chemistry
  • 90D - Biology & Medicine
  • 99D - Basic & Synthetic Chemistry
  • 57Q - Pharmacology & Pharmacological Chemistry
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