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The Toxicology of DMMPA. Part I. The Acute Effects of DMMPA.


ADA044988

Publication Date 1977
Personal Author Coleman, I. W.
Page Count 56
Abstract The toxicological properties of dimethyl morpholinophosphoramidate (DMMPA) have been examined in mice, rats and rabbits using a variety of criteria of toxicological responses. Nutritional, physiological, haematological and blood serum components were studied after DMMPA acute dosing. Macroscopic and microscopic pathology was also carried out. The maximum dose causing no pathological effects was in no case less than the LD(o) dose estimate, indicating the compound was remarkably free of pathological effect, and likely indicating the compound to be safe for acute exposures of small amounts to man. (Author)
Keywords
  • Toxicology
  • Morpholine
  • Organic phosphorus compounds
  • Organic nitrogen compounds
  • Mice
  • Rats
  • Rabbits
  • Nutrition
  • Physiology
  • Blood serum
  • Hematology
  • Pathology
  • Dosage
  • Recovery
  • Tissues(Biology)
  • Time
  • Methyl radicals
  • Response(Biology)
  • DMMPA(Dimethyl Morpholinophosphoramidate)
  • Morpholinophosphoramidate/dimethyl
Source Agency
  • Non Paid ADAS
NTIS Subject Category
  • 57Y - Toxicology
Corporate Authors Defence Research Establishment Suffield Ralston (Alberta)
Supplemental Notes See also Part 2, AD-A044 751.
Document Type Technical Report
NTIS Issue Number 197726
The Toxicology of DMMPA. Part I. The Acute Effects of DMMPA.
The Toxicology of DMMPA. Part I. The Acute Effects of DMMPA.
ADA044988

  • Toxicology
  • Morpholine
  • Organic phosphorus compounds
  • Organic nitrogen compounds
  • Mice
  • Rats
  • Rabbits
  • Nutrition
  • Physiology
  • Blood serum
  • Hematology
  • Pathology
  • Dosage
  • Recovery
  • Tissues(Biology)
  • Time
  • Methyl radicals
  • Response(Biology)
  • DMMPA(Dimethyl Morpholinophosphoramidate)
  • Morpholinophosphoramidate/dimethyl
  • Non Paid ADAS
  • 57Y - Toxicology
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