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Tilt Table Response of Human Subjects Following Application of Lower Body Negative Pressure.

AD698010

Publication Date	1966
Personal Author	McCally, M.; Piemme, T. E.; Murray, R. H.
Page Count	6
Abstract	Orthostatic tachycardia and hypotension are known consequences of bed rest in normal subjects. This response is felt to follow from the reduction in plasma volume accompanying the salt and water diuresis of recumbency. Similar effects are felt to result from zero gravity during manned space flight. Lower body negative pressure (LBNP) has been suggested as a countermeasure to such adverse effects of weightlessness. Tilt table test responses were measured in six subjects after exposure to two conditions of LBNP. Six hours of intermittent (one minute on, one minute off) LBNP (55 mm. Hg) prevents the orthostatic tachycardia of six hours of bed rest. A continuous ninety minute LBNP (30 mm. Hg) exposure improves the tilt response to better than control values. These data support the proposal that LBNP may be useful in maintaining the orthostatic tolerance of confined and weightless astronauts. (Author)
Keywords	Weightlessness Heart Blood pressure Barometric pressure Hypotension Responses Space flight Exposure Blood circulation Blood plasma Measurement Reprints Heart rate
NTIS Subject Category	57W - Stress Physiology 57S - Physiology
Corporate Authors	Aerospace Medical Research Lab Wright-Patterson AFB Ohio
Document Type	Journal Article
NTIS Issue Number	197003

Tilt Table Response of Human Subjects Following Application of Lower Body Negative Pressure.

Tilt Table Response of Human Subjects Following Application of Lower Body Negative Pressure.
AD698010

Publication Date	1966
Personal Author	McCally, M.; Piemme, T. E.; Murray, R. H.
Page Count	6
Abstract	Orthostatic tachycardia and hypotension are known consequences of bed rest in normal subjects. This response is felt to follow from the reduction in plasma volume accompanying the salt and water diuresis of recumbency. Similar effects are felt to result from zero gravity during manned space flight. Lower body negative pressure (LBNP) has been suggested as a countermeasure to such adverse effects of weightlessness. Tilt table test responses were measured in six subjects after exposure to two conditions of LBNP. Six hours of intermittent (one minute on, one minute off) LBNP (55 mm. Hg) prevents the orthostatic tachycardia of six hours of bed rest. A continuous ninety minute LBNP (30 mm. Hg) exposure improves the tilt response to better than control values. These data support the proposal that LBNP may be useful in maintaining the orthostatic tolerance of confined and weightless astronauts. (Author)
Keywords	Weightlessness Heart Blood pressure Barometric pressure Hypotension Responses Space flight Exposure Blood circulation Blood plasma Measurement Reprints Heart rate
NTIS Subject Category	57W - Stress Physiology 57S - Physiology
Corporate Authors	Aerospace Medical Research Lab Wright-Patterson AFB Ohio
Document Type	Journal Article
NTIS Issue Number	197003